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product-image-AAA46313_IHC11.jpg IHC (Immunohistochemisry) (Anti- Galectin3 Picoband antibody, AAA46313, IHC(P)IHC(P): Rat Intestine Tissue)

anti-Mouse, Rat Galectin 3 Polyclonal Antibody | anti-Lgals3 antibody

Anti-Galectin 3 Antibody

Gene Names
Lgals3; GBP; L-34; gal3; Mac-2
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
Galectin 3, Antibody; Anti-Galectin 3 Antibody; Galectin-3; 35 kDa lectin; Carbohydrate binding protein 35; Carbohydrate-binding protein 35; CBP 35; CBP35; GAL 3; Gal-3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin 3 internal gene,included; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-31; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LEG3_HUMAN; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; Mac-2 antigen; MAC2; Macrophage galactose-specific lectin; MGC105387; lectin, galactoside-binding, soluble, 3; anti-Lgals3 antibody
Ordering
Reactivity
Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
264
Applicable Applications for anti-Lgals3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived mouse Galectin 3 recombinant protein (Position: K153-I264). Mouse Galectin 3 shares 88% and 91% amino acid (aa) sequence identity with human and rat Galectin 3, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

IHC (Immunohistochemisry)

(Anti- Galectin3 Picoband antibody, AAA46313, IHC(P)IHC(P): Rat Intestine Tissue)

product-image-AAA46313_IHC11.jpg IHC (Immunohistochemisry) (Anti- Galectin3 Picoband antibody, AAA46313, IHC(P)IHC(P): Rat Intestine Tissue)

IHC (Immunohiostchemistry)

(Anti- Galectin3 Picoband antibody, AAA46313, IHC(P)IHC(P): Mouse Spleen Tissue)

product-image-AAA46313_IHC13.jpg IHC (Immunohiostchemistry) (Anti- Galectin3 Picoband antibody, AAA46313, IHC(P)IHC(P): Mouse Spleen Tissue)

WB (Western Blot)

(Anti- Galectin3 Picoband antibody, AAA46313, Western blottingAll lanes: Anti Galectin3 (AAA46313) at 0.5ug/mlLane 1: Mouse Kidney Tissue Lysate at 50ugLane 2: Mouse Liver Tissue Lysate at 50ugLane 3: Mouse Spleen Tissue Lysate at 50ugLane 4: Mouse Ovary Tissue Lysate at 50ugLane 5: HEPA Whole Cell Lysate at 40ugLane 6: ANA-1 Whole Cell Lysate at 40ugLane 7: NIH3T3 Whole Cell Lysate at 40ugredicted bind size: 26KDObserved bind size: 26KD)

product-image-AAA46313_WB15.jpg WB (Western Blot) (Anti- Galectin3 Picoband antibody, AAA46313, Western blottingAll lanes: Anti Galectin3 (AAA46313) at 0.5ug/mlLane 1: Mouse Kidney Tissue Lysate at 50ugLane 2: Mouse Liver Tissue Lysate at 50ugLane 3: Mouse Spleen Tissue Lysate at 50ugLane 4: Mouse Ovary Tissue Lysate at 50ugLane 5: HEPA Whole Cell Lysate at 40ugLane 6: ANA-1 Whole Cell Lysate at 40ugLane 7: NIH3T3 Whole Cell Lysate at 40ugredicted bind size: 26KDObserved bind size: 26KD)
Related Product Information for anti-Lgals3 antibody
Description: Rabbit IgG polyclonal antibody for Galectin-3(LGALS3) detection. Tested with WB, IHC-P in Mouse;Rat.

Background: Galectin-3(GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.
References
1. Dumic J, Dabelic S, Flögel M. (2006). "Galectin-3: an open-ended story.". BBA General Subjects 1760(4): 616-635. 2. Liu F, Patterson RJ, Wang JL. (2002). "Intracellular function of galectins.". BBA General Subjects 1572 (2-3): 263-273. 3. Cooper D. (2002). "Galectinomics: finding themes in complexity.". BBA General Subjects 1572 (2-3): 209-231. 4. Raimond J, Zimonjic DB, Mignon C, et al. (1997). "Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21—22.". Mamm. Genome 8 (9): 706-707.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
27,515 Da
NCBI Official Full Name
Galectin-3
NCBI Official Synonym Full Names
lectin, galactose binding, soluble 3
NCBI Official Symbol
Lgals3
NCBI Official Synonym Symbols
GBP; L-34; gal3; Mac-2
NCBI Protein Information
galectin-3
UniProt Protein Name
Galectin-3
UniProt Gene Name
Lgals3
UniProt Synonym Gene Names
Gal-3; CBP 35
UniProt Entry Name
LEG3_MOUSE

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Product Notes

The Lgals3 lgals3 (Catalog #AAA46313) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Galectin 3 Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Galectin 3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Lgals3 lgals3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galectin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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