IHC (Immunohiostchemistry)
(GDI2 Antibody (Center) (AAA284394)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human GDI2 Polyclonal Antibody | anti-GDI2 antibody
GDI2 Antibody (Center)
Gene Names
GDI2; RABGDIB; HEL-S-46e
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GDI2, Antibody; GDI2 Antibody (Center); Rab GDP dissociation inhibitor beta; Rab GDI beta; Guanosine diphosphate dissociation inhibitor 2; GDI-2; GDI2; RABGDIB; anti-GDI2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GDI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human GDI2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
135-164
Sequence Length
400
Applicable Applications for anti-GDI2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(GDI2 Antibody (Center) (AAA284394)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(GDI2 Antibody (Center) (AAA284394)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(GDI2 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GDI2 antibody detected the GDI2 protein (arrow).)
WB (Western Blot)
(GDI2 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GDI2 antibody detected the GDI2 protein (arrow).)
Related Product Information for anti-GDI2 antibody
GDP dissociation inhibitors are proteins that regulate the
GDP-GTP exchange reaction of members of the rab family, small
GTP-binding proteins of the ras superfamily, that are involved in
vesicular trafficking of molecules between cellular organelles.
GDIs slow the rate of dissociation of GDP from rab proteins and
release GDP from membrane-bound rabs. GDI2 is ubiquitously
expressed. The GDI2 gene contains many repetitive elements
indicating that it may be prone to inversion/deletion
rearrangements. Alternative splicing results in multiple transcript
variants encoding distinct isoforms.
GDP-GTP exchange reaction of members of the rab family, small
GTP-binding proteins of the ras superfamily, that are involved in
vesicular trafficking of molecules between cellular organelles.
GDIs slow the rate of dissociation of GDP from rab proteins and
release GDP from membrane-bound rabs. GDI2 is ubiquitously
expressed. The GDI2 gene contains many repetitive elements
indicating that it may be prone to inversion/deletion
rearrangements. Alternative splicing results in multiple transcript
variants encoding distinct isoforms.
Product Categories/Family for anti-GDI2 antibody
References
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Sun, Z.L., et al. Biochim. Biophys. Acta 1774(6):764-771(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Shin, B.K., et al. J. Biol. Chem. 278(9):7607-7616(2003)
Sun, Z.L., et al. Biochim. Biophys. Acta 1774(6):764-771(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Shin, B.K., et al. J. Biol. Chem. 278(9):7607-7616(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50663
NCBI Official Full Name
rab GDP dissociation inhibitor beta isoform 2
NCBI Official Synonym Full Names
GDP dissociation inhibitor 2
NCBI Official Symbol
GDI2
NCBI Official Synonym Symbols
RABGDIB; HEL-S-46e
NCBI Protein Information
rab GDP dissociation inhibitor beta
UniProt Protein Name
Rab GDP dissociation inhibitor beta
UniProt Gene Name
GDI2
UniProt Synonym Gene Names
RABGDIB; Rab GDI beta; GDI-2
UniProt Entry Name
GDIB_HUMAN
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Product Notes
The GDI2 gdi2 (Catalog #AAA284394) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 135-164. The GDI2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GDI2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GDI2 gdi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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