IHC (Immunohiostchemistry)
(HAX1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HAX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human HAX1 Polyclonal Antibody | anti-HAX1 antibody
HAX1 Antibody (C-term)
Gene Names
HAX1; SCN3; HS1BP1; HCLSBP1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HAX1, Antibody; HAX1 Antibody (C-term); HCLS1-associated protein X-1; HS1-associating protein X-1; HAX-1; HS1-binding protein 1; HSP1BP-1; HAX1; HS1BP1; anti-HAX1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the C-terminal region of human HAX1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.25 (varies by lot)
Sequence Positions
161-190
Sequence Length
191
Applicable Applications for anti-HAX1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(HAX1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HAX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(HAX1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HAX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(HAX1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HAX1 antibody detected the HAX1 protein (arrow).)
WB (Western Blot)
(HAX1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HAX1 antibody detected the HAX1 protein (arrow).)
Related Product Information for anti-HAX1 antibody
The protein encoded by this gene is known to associate
with hematopoietic cell-specific Lyn substrate 1, a substrate of
Src family tyrosine kinases. It also interacts with the product of
the polycystic kidney disease 2 gene, mutations in which are
associated with autosomal-dominant polycystic kidney disease, and
with the F-actin-binding protein, cortactin. It was earlier thought
that this gene product is mainly localized in the mitochondria,
however, recent studies indicate it to be localized in the cell
body. Mutations in this gene result in autosomal recessive severe
congenital neutropenia, also known as Kostmann disease. Two
transcript variants encoding different isoforms have been found for
this gene.
with hematopoietic cell-specific Lyn substrate 1, a substrate of
Src family tyrosine kinases. It also interacts with the product of
the polycystic kidney disease 2 gene, mutations in which are
associated with autosomal-dominant polycystic kidney disease, and
with the F-actin-binding protein, cortactin. It was earlier thought
that this gene product is mainly localized in the mitochondria,
however, recent studies indicate it to be localized in the cell
body. Mutations in this gene result in autosomal recessive severe
congenital neutropenia, also known as Kostmann disease. Two
transcript variants encoding different isoforms have been found for
this gene.
Product Categories/Family for anti-HAX1 antibody
References
Johns, H.L., et al. J. Gen. Virol. 91 (PT 11), 2677-2686 (2010) :
Mekkawy, A.H., et al. Biochem. Biophys. Res. Commun. 399(4):738-743(2010)
Han, J., et al. J. Biol. Chem. 285(29):22461-22472(2010)
Germeshausen, M., et al. Haematologica 95(7):1207-1210(2010)
Burnicka-Turek, O., et al. BMC Cell Biol. 11, 28 (2010) :
Mekkawy, A.H., et al. Biochem. Biophys. Res. Commun. 399(4):738-743(2010)
Han, J., et al. J. Biol. Chem. 285(29):22461-22472(2010)
Germeshausen, M., et al. Haematologica 95(7):1207-1210(2010)
Burnicka-Turek, O., et al. BMC Cell Biol. 11, 28 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31621
NCBI Official Full Name
HCLS1-associated protein X-1 isoform b
NCBI Official Synonym Full Names
HCLS1 associated protein X-1
NCBI Official Symbol
HAX1
NCBI Official Synonym Symbols
SCN3; HS1BP1; HCLSBP1
NCBI Protein Information
HCLS1-associated protein X-1
UniProt Protein Name
HCLS1-associated protein X-1
UniProt Gene Name
HAX1
UniProt Synonym Gene Names
HS1BP1; HAX-1; HSP1BP-1
UniProt Entry Name
HAX1_HUMAN
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Product Notes
The HAX1 hax1 (Catalog #AAA287145) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 161-190. The HAX1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HAX1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the HAX1 hax1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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