IHC (Immunohiostchemistry)
(HSD17B4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSD17B4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human HSD17B4 Polyclonal Antibody | anti-HSD17B4 antibody
HSD17B4 Antibody (Center)
Gene Names
HSD17B4; DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HSD17B4, Antibody; HSD17B4 Antibody (Center); Peroxisomal multifunctional enzyme type 2; MFE-2; 17-beta-hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; D-bifunctional protein; DBP; Multifunctional protein 2; MPF-2; (3R)-hydroxyacyl-CoA dehydrogenase; 111n12; Enoyl-CoA hydratase 2; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; HSD17B4; EDH17B4; anti-HSD17B4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HSD17B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the Central region of human HSD17B4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.25 (varies by lot)
Sequence Positions
341-370
Sequence Length
718
Applicable Applications for anti-HSD17B4 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(HSD17B4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSD17B4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(HSD17B4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HSD17B4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(HSD17B4 Antibody (Center) western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).This demonstrates the HSD17B4 antibody detected the HSD17B4 protein (arrow).)
WB (Western Blot)
(HSD17B4 Antibody (Center) western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).This demonstrates the HSD17B4 antibody detected the HSD17B4 protein (arrow).)
Related Product Information for anti-HSD17B4 antibody
The protein encoded by this gene is a bifunctional enzyme
that is involved in the peroxisomal beta-oxidation pathway for
fatty acids. It also acts as a catalyst for the formation of
3-ketoacyl-CoA intermediates from both straight-chain and
2-methyl-branched-chain fatty acids. Defects in this gene that
affect the peroxisomal fatty acid beta-oxidation activity are a
cause of D-bifunctional protein deficiency (DBPD). An apparent
pseudogene of this gene is present on chromosome 8. [provided by
RefSeq].
that is involved in the peroxisomal beta-oxidation pathway for
fatty acids. It also acts as a catalyst for the formation of
3-ketoacyl-CoA intermediates from both straight-chain and
2-methyl-branched-chain fatty acids. Defects in this gene that
affect the peroxisomal fatty acid beta-oxidation activity are a
cause of D-bifunctional protein deficiency (DBPD). An apparent
pseudogene of this gene is present on chromosome 8. [provided by
RefSeq].
Product Categories/Family for anti-HSD17B4 antibody
References
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kashiwayama, Y., et al. J. Biol. Chem. 285(34):26315-26325(2010)
Pierce, S.B., et al. Am. J. Hum. Genet. 87(2):282-288(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Kashiwayama, Y., et al. J. Biol. Chem. 285(34):26315-26325(2010)
Pierce, S.B., et al. Am. J. Hum. Genet. 87(2):282-288(2010)
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
79686
NCBI Official Full Name
peroxisomal multifunctional enzyme type 2 isoform 2
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 4
NCBI Official Symbol
HSD17B4
NCBI Official Synonym Symbols
DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
NCBI Protein Information
peroxisomal multifunctional enzyme type 2
UniProt Protein Name
Peroxisomal multifunctional enzyme type 2
UniProt Gene Name
HSD17B4
UniProt Synonym Gene Names
EDH17B4; SDR8C1; MFE-2; 17-beta-HSD 4; DBP; MPF-2
UniProt Entry Name
DHB4_HUMAN
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Product Notes
The HSD17B4 hsd17b4 (Catalog #AAA289904) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 341-370. The HSD17B4 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HSD17B4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the HSD17B4 hsd17b4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSD17B4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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