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product-image-AAA301159_IHC13.gif IHC (Immunohiostchemistry) (Immunohistochemistry of IEX-1 in human liver tissue with IEX-1 antibody at 2.5 ug/mL.)

Rabbit anti-Human, Mouse IEX-1 Polyclonal Antibody | anti-IEX-1 antibody

IEX-1 Antibody

Gene Names
IER3; DIF2; IEX1; PRG1; DIF-2; GLY96; IEX-1; IEX-1L
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
IEX-1, Antibody; IEX-1 Antibody; Immediate early response 3, IER3, DIF2, PRG1, GLY96; anti-IEX-1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
156
Applicable Applications for anti-IEX-1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 24 amino acid peptide near the center of human IEX1.
Target Name
IEX-1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IHC (Immunohiostchemistry)

(Immunohistochemistry of IEX-1 in human liver tissue with IEX-1 antibody at 2.5 ug/mL.)

product-image-AAA301159_IHC13.gif IHC (Immunohiostchemistry) (Immunohistochemistry of IEX-1 in human liver tissue with IEX-1 antibody at 2.5 ug/mL.)

WB (Western Blot)

(Western blot analysis of IEX1 in human brain tissue lysate with IEX1 antibody at (A) 2 and (B) 4 ug/mL.)

product-image-AAA301159_WB15.gif WB (Western Blot) (Western blot analysis of IEX1 in human brain tissue lysate with IEX1 antibody at (A) 2 and (B) 4 ug/mL.)
Related Product Information for anti-IEX-1 antibody
IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progression, whereas disruption of IEX-1 expression is associated with decreases in both apoptosis and cell cycle progression.
Product Categories/Family for anti-IEX-1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,903 Da
NCBI Official Full Name
radiation-inducible immediate-early gene IEX-1
NCBI Official Synonym Full Names
immediate early response 3
NCBI Official Symbol
IER3
NCBI Official Synonym Symbols
DIF2; IEX1; PRG1; DIF-2; GLY96; IEX-1; IEX-1L
NCBI Protein Information
radiation-inducible immediate-early gene IEX-1
UniProt Protein Name
Radiation-inducible immediate-early gene IEX-1
UniProt Gene Name
IER3
UniProt Synonym Gene Names
DIF2; IEX1; PRG1; Protein DIF-2; Protein PRG1
UniProt Entry Name
IEX1_HUMAN

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Product Notes

The IEX-1 ier3 (Catalog #AAA301159) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IEX-1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IEX-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IEX-1 ier3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IEX-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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