IHC (Immunohiostchemistry)
(KCNA1 Antibody (Center) (AAA290372)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNA1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit KCNA1 Polyclonal Antibody | anti-KCNA1 antibody
KCNA1 Antibody (Center)
Gene Names
KCNA1; EA1; MK1; AEMK; HBK1; HUK1; MBK1; RBK1; KV1.1
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KCNA1, Antibody; KCNA1 Antibody (Center); Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv11; KCNA1; anti-KCNA1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This KCNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the Central region of human KCNA1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.3 (varies by lot)
Sequence Positions
172-201
Sequence Length
495
Applicable Applications for anti-KCNA1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(KCNA1 Antibody (Center) (AAA290372)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNA1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(KCNA1 Antibody (Center) (AAA290372)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNA1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(KCNA1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KCNA1 antibody detected the KCNA1 protein (arrow).)
WB (Western Blot)
(KCNA1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KCNA1 antibody detected the KCNA1 protein (arrow).)
Related Product Information for anti-KCNA1 antibody
This gene encodes a voltage-gated delayed potassium
channel that is phylogenetically related to the Drosophila Shaker
channel. The encoded protein has six putative transmembrane
segments (S1-S6), and the loop between S5 and S6 forms the pore and
contains the conserved selectivity filter motif (GYGD). The
functional channel is a homotetramer. The N-terminus of the channel
is associated with beta subunits that can modify the inactivation
properties of the channel as well as affect expression levels. The
C-terminus of the channel is complexed to a PDZ domain protein that
is responsible for channel targeting. Mutations in this gene have
been associated with myokymia with periodic ataxia (AEMK).
channel that is phylogenetically related to the Drosophila Shaker
channel. The encoded protein has six putative transmembrane
segments (S1-S6), and the loop between S5 and S6 forms the pore and
contains the conserved selectivity filter motif (GYGD). The
functional channel is a homotetramer. The N-terminus of the channel
is associated with beta subunits that can modify the inactivation
properties of the channel as well as affect expression levels. The
C-terminus of the channel is complexed to a PDZ domain protein that
is responsible for channel targeting. Mutations in this gene have
been associated with myokymia with periodic ataxia (AEMK).
Product Categories/Family for anti-KCNA1 antibody
References
Graves, T.D., et al. Neurology 75(4):367-372(2010)
Bailey, S.D., et al. Diabetes Care (2010) In press :
van der Wijst, J., et al. J. Biol. Chem. 285(1):171-178(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kim, E., et al. Nature 378(6552):85-88(1995)
Bailey, S.D., et al. Diabetes Care (2010) In press :
van der Wijst, J., et al. J. Biol. Chem. 285(1):171-178(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kim, E., et al. Nature 378(6552):85-88(1995)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56466
NCBI Official Full Name
potassium voltage-gated channel subfamily A member 1
NCBI Official Synonym Full Names
potassium channel, voltage gated shaker related subfamily A, member 1
NCBI Official Symbol
KCNA1
NCBI Official Synonym Symbols
EA1; MK1; AEMK; HBK1; HUK1; MBK1; RBK1; KV1.1
NCBI Protein Information
potassium voltage-gated channel subfamily A member 1
UniProt Protein Name
Potassium voltage-gated channel subfamily A member 1
UniProt Gene Name
KCNA1
UniProt Entry Name
KCNA1_HUMAN
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Product Notes
The KCNA1 kcna1 (Catalog #AAA290372) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 172-201. The KCNA1 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's KCNA1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KCNA1 kcna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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