WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using KDM2A Antibody. The lane on the left was treated with blocking peptide.)
Rabbit anti-Human, Mouse KDM2A Polyclonal Antibody | anti-KDM2A antibody
KDM2A Antibody
Gene Names
KDM2A; FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Peptide affinity purification
Synonyms
KDM2A, Antibody; KDM2A Antibody; [Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; CXXC8; F box/LRR repeat protein 11; F box and leucine rich repeat protein 11; F box protein FBL7; F-box and leucine-rich repeat protein 11; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; FBL11; FBL7; FBXL11; JHDM1A; JmjC domain-containing histone demethylation protein 1A; Jumonji C domain containing histone demethylase 1A; kdm2a; KDM2A_HUMAN; LILINA; Lysine (K) specific demethylase 2A; Lysine-specific demethylase 2A; anti-KDM2A antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
KDM2A Antibody detects endogenous levels of KDM2A.
Purity/Purification
Peptide affinity purification
Form/Format
IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-KDM2A antibody
ELISA, WB (Western Blot)
Immunogen
A synthesized peptide derived from human KDM2A, corresponding to a region within the internal amino acids.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using KDM2A Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using KDM2A Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-KDM2A antibody
Description: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
Subunit Structure: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity). Interacts with CBX5/HP1A; the interaction promotes CBX5 localization to chromatin.
Similarity: The JmjC domain mediates demethylation activity and is required for satellite silencing. The CXXC zinc finger preferentially recognizes nonmethylated CpG DNA, and binding is blocked when the CpG DNA is methylated. Belongs to the JHDM1 histone demethylase family.
Subunit Structure: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity). Interacts with CBX5/HP1A; the interaction promotes CBX5 localization to chromatin.
Similarity: The JmjC domain mediates demethylation activity and is required for satellite silencing. The CXXC zinc finger preferentially recognizes nonmethylated CpG DNA, and binding is blocked when the CpG DNA is methylated. Belongs to the JHDM1 histone demethylase family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
126kDa
NCBI Official Full Name
lysine-specific demethylase 2A isoform a
NCBI Official Synonym Full Names
lysine demethylase 2A
NCBI Official Symbol
KDM2A
NCBI Official Synonym Symbols
FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA
NCBI Protein Information
lysine-specific demethylase 2A
UniProt Protein Name
Lysine-specific demethylase 2A
UniProt Gene Name
KDM2A
UniProt Synonym Gene Names
CXXC8; FBL7; FBXL11; JHDM1A; KIAA1004
UniProt Entry Name
KDM2A_HUMAN
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Product Notes
The KDM2A kdm2a (Catalog #AAA328862) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDM2A Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KDM2A can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KDM2A kdm2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDM2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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