IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)
Rabbit anti-Human, Mouse KDM3B Polyclonal Antibody | anti-KDM3B antibody
KDM3B Antibody
Gene Names
KDM3B; 5qNCA; NET22; C5orf7; JMJD1B
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
KDM3B, Antibody; KDM3B Antibody; 5qNCA; NET22; C5orf7; JMJD1B; anti-KDM3B antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total KDM3B protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2 mg/ml (varies by lot)
Sequence Length
1761
Applicable Applications for anti-KDM3B antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human lysine (K)-specific demethylase 3B
Target Name
KDM3B
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)
Application Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Hela and 293T cell, mouse skeletal muscle tissue Amount of lysate: 40ug per lane Primary antibody: 1/1000 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Application Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Hela and 293T cell, mouse skeletal muscle tissue Amount of lysate: 40ug per lane Primary antibody: 1/1000 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Related Product Information for anti-KDM3B antibody
JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
Product Categories/Family for anti-KDM3B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,712 Da
NCBI Official Full Name
lysine-specific demethylase 3B
NCBI Official Synonym Full Names
lysine (K)-specific demethylase 3B
NCBI Official Symbol
KDM3B
NCBI Official Synonym Symbols
5qNCA; NET22; C5orf7; JMJD1B
NCBI Protein Information
lysine-specific demethylase 3B
UniProt Protein Name
Lysine-specific demethylase 3B
UniProt Gene Name
KDM3B
UniProt Synonym Gene Names
C5orf7; JHDM2B; JMJD1B; KIAA1082
UniProt Entry Name
KDM3B_HUMAN
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Product Notes
The KDM3B kdm3b (Catalog #AAA305516) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDM3B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KDM3B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KDM3B kdm3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDM3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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