Rabbit JMJD1B Polyclonal Antibody | anti-KDM3B antibody

JMJD1B Antibody

Cat. Num. AAA39217

• Gene Names: KDM3B; 5qNCA; NET22; C5orf7; JMJD1B
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: JMJD1B Antibody is affinity chromatography purified via peptide column.
• Synonyms: JMJD1B, Antibody; JMJD1B Antibody; JMJD1B; 5qNCA; NET22; C5orf7; JHDM2B; KIAA1082; Lysine-specific demethylase 3B; JmjC domain-containing histone demethylation protein 2B; lysine (K)-specific demethylase 3B; anti-KDM3B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This antibody will not cross-react with JMJD1A or JMJD1C.
• Purity/Purification: JMJD1B Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1761

• Applicable Applications for anti-KDM3B antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: JMJD1B antibody was raised against a 20 amino acid synthetic peptide from near the center of human JMJD1B.
• Buffer: JMJD1B Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: JMJD1B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of JMJD1B in rat liver tissue with JMJD1B antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of JMJD1B in rat liver tissue with JMJD1B antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of JMJD1B in rat liver tissue lysate with JMJD1B antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-KDM3B antibody

JMJD1B Antibody: The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist.

NCBI and Uniprot Product Information

• NCBI GI #: 119582545
• NCBI GeneID: 51780
• UniProt Accession #: Q7LBC6; Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0; A6H8X7
• Molecular Weight: 84,712 Da
• NCBI Official Full Name: jumonji domain containing 1B, isoform CRA_a
• NCBI Official Synonym Full Names: lysine (K)-specific demethylase 3B
• NCBI Official Symbol: KDM3B
• NCBI Official Synonym Symbols: 5qNCA; NET22; C5orf7; JMJD1B
• NCBI Protein Information: lysine-specific demethylase 3B; nuclear protein 5qNCA; jumonji domain containing 1B; jumonji domain-containing protein 1B; jmjC domain-containing histone demethylation protein 2B
• UniProt Protein Name: Lysine-specific demethylase 3B
• UniProt Gene Name: KDM3B
• UniProt Synonym Gene Names: C5orf7; JHDM2B; JMJD1B; KIAA1082
• UniProt Entry Name: KDM3B_HUMAN