IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/50.)
Rabbit anti-Human KDM4D Polyclonal Antibody | anti-KDM4D antibody
KDM4D Antibody
Gene Names
KDM4D; JMJD2D
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
KDM4D, Antibody; KDM4D Antibody; JMJD2D; anti-KDM4D antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total KDM4D protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.2 mg/ml (varies by lot)
Sequence Length
523
Applicable Applications for anti-KDM4D antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 4D
Target Name
KDM4D
Preparation and Storage
Store at -20°C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/50.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/50.)
Application Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Human fetal brain tissue Amount of lysate: 40ug per lane Primary antibody: 1/1100 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes)
Application Data
(Gel: 8%SDS-PAGE Lysates (from left to right): Human fetal brain tissue Amount of lysate: 40ug per lane Primary antibody: 1/1100 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 minutes)
Related Product Information for anti-KDM4D antibody
JMJD2D (Jumonji domain-containing protein 2D), also known as JHDM3D or KDM4D, is a 520 amino acid protein that belongs to the JHDM3 histone demethylase family. Localized to the nucleus, JMJD2D functions as a histone demethylase that removes specific methyl residues from Histone H3, thereby playing a crucial role in the histone code. JMJD2D binds iron as a cofactor and contains one JMJC domain and one JMJN domain, both of which are thought to exhibit enzymatic activity during chromatin remodeling events. In addition, JMJD2D forms a complex with the ligand-bound form of the androgen receptor (AR) and, through this interaction, activates AR expression. Overexpression of AR is associated with prostate cancer, suggesting that, via its ability to upregulate AR, JMJD2D may be involved in carcinogenesis.
Product Categories/Family for anti-KDM4D antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
SDS-PAGE MW: 59kd
NCBI Official Full Name
lysine-specific demethylase 4D
NCBI Official Synonym Full Names
lysine (K)-specific demethylase 4D
NCBI Official Symbol
KDM4D
NCBI Official Synonym Symbols
JMJD2D
NCBI Protein Information
lysine-specific demethylase 4D
UniProt Protein Name
Lysine-specific demethylase 4D
UniProt Gene Name
KDM4D
UniProt Synonym Gene Names
JHDM3D; JMJD2D
UniProt Entry Name
KDM4D_HUMAN
Similar Products
Product Notes
The KDM4D kdm4d (Catalog #AAA301014) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KDM4D Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KDM4D can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KDM4D kdm4d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KDM4D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.