Rabbit LMX1B Polyclonal Antibody | anti-LMX1B antibody

LMX1B Antibody

Cat. Num. AAA40768

• Gene Names: LMX1B; NPS1; LMX1.2
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: LMX1B Antibody is affinity chromatography purified via peptide column.
• Synonyms: LMX1B, Antibody; LMX1B Antibody; LMX1B; NPS1; LMX1.2; LIM homeobox transcription factor 1-beta; LIM homeobox transcription factor 1, beta; anti-LMX1B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A.
• Purity/Purification: LMX1B Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 406

• Applicable Applications for anti-LMX1B antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B.
• Buffer: LMX1B Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: LMX1B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of LMX1B in mouse brain tissue with LMX1B Antibody at 20 μg/mL.Green: LMX1B antibody (7089)Red: Phylloidin stainingBlue: DAPI staining)

IHC (Immunohistochemistry)

(Immunohistochemistry of LMX1B in mouse brain tissue with LMX1B Antibody at 5 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of LMX1B in human brain tissue with LMX1B antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of LMX1B in human brain tissue with LMX1B antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of LMX1B in A-20 cell lysate with LMX1B antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-LMX1B antibody

LMX1B Antibody: The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.

NCBI and Uniprot Product Information

• NCBI GI #: 292494913
• NCBI GeneID: 4010
• NCBI Accession #: NP_001167617
• NCBI GenBank Nucleotide #: NM_001174146.1
• UniProt Accession #: O60663; O75463; Q5JU95; Q6ISC9; F8W7W6
• Molecular Weight: 45 kDa
• NCBI Official Full Name: LIM homeobox transcription factor 1-beta isoform 3
• NCBI Official Synonym Full Names: LIM homeobox transcription factor 1, beta
• NCBI Official Symbol: LMX1B
• NCBI Official Synonym Symbols: NPS1; LMX1.2
• NCBI Protein Information: LIM homeobox transcription factor 1-beta; LMX-1.2; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B
• UniProt Protein Name: LIM homeobox transcription factor 1-beta
• UniProt Gene Name: LMX1B
• UniProt Synonym Gene Names: LMX-1.2
• UniProt Entry Name: LMX1B_HUMAN