WB (Western Blot)
(Western blot analysis of LMX1B (arrow) using rabbit polyclonal LMX1B Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LMX1B gene.)
Rabbit LMX1B Polyclonal Antibody | anti-LMX1B antibody
LMX1B Antibody (Center)
Gene Names
LMX1B; NPS1; LMX1.2
Reactivity
Human, mouse (Predicted Reactivity: Chicken, Xenopus)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
LMX1B, Antibody; LMX1B Antibody (Center); LIM homeobox transcription factor 1-beta; LIM/homeobox protein 12; LMX-12; LIM/homeobox protein LMX1B; LMX1B; anti-LMX1B antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Chicken, Xenopus)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LMX1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the Central region of human LMX1B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
175-202
Sequence Length
402
Applicable Applications for anti-LMX1B antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of LMX1B (arrow) using rabbit polyclonal LMX1B Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LMX1B gene.)
WB (Western Blot)
(Western blot analysis of LMX1B (arrow) using rabbit polyclonal LMX1B Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LMX1B gene.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human testis tissue reacted with LMX1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human testis tissue reacted with LMX1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of LMX1B Antibody (Center) in mouse heart tissue lysates (35ug/lane). LMX1B (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of LMX1B Antibody (Center) in mouse heart tissue lysates (35ug/lane). LMX1B (arrow) was detected using the purified Pab.)
Related Product Information for anti-LMX1B antibody
LMX1B is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.
Product Categories/Family for anti-LMX1B antibody
References
Ham,J.H., et.al., Korean J. Intern. Med. 24 (3), 274-278 (2009)
Bergman,O., et.al., J Neural Transm 116 (3), 333-338 (2009)
Bergman,O., et.al., J Neural Transm 116 (3), 333-338 (2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44917
NCBI Official Full Name
LIM homeobox transcription factor 1-beta isoform 2
NCBI Official Synonym Full Names
LIM homeobox transcription factor 1, beta
NCBI Official Symbol
LMX1B
NCBI Official Synonym Symbols
NPS1; LMX1.2
NCBI Protein Information
LIM homeobox transcription factor 1-beta
UniProt Protein Name
LIM homeobox transcription factor 1-beta
UniProt Gene Name
LMX1B
UniProt Synonym Gene Names
LMX-1.2
UniProt Entry Name
LMX1B_HUMAN
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Product Notes
The LMX1B lmx1b (Catalog #AAA288687) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 175-202. The LMX1B Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Chicken, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's LMX1B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the LMX1B lmx1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LMX1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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