IHC (Immunohiostchemistry)
(Immunohistochemistry of LRRTM3 in human brain tissue with LRRTM3 antibody at 2.5 ug/mL)
Rabbit LRRTM3 Polyclonal Antibody | anti-LRRTM3 antibody
LRRTM3 Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
LRRTM3, Antibody; LRRTM3 Antibody; Leucine-rich repeat transmembrane neuronal protein 3; anti-LRRTM3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
At least two isoforms of LRRTM3 are known to exist; this antibody will only detect the larger isoform.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
581
Applicable Applications for anti-LRRTM3 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 18 amino acid peptide near the carboxy terminus of human LRRTM3.
Target Name
LRRTM3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of LRRTM3 in human brain tissue with LRRTM3 antibody at 2.5 ug/mL)
IHC (Immunohiostchemistry)
(Immunohistochemistry of LRRTM3 in human brain tissue with LRRTM3 antibody at 2.5 ug/mL)
WB (Western Blot)
(Western blot analysis of LRRTM3 in mouse brain tissue lysate with LRRTM3 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of LRRTM3 in mouse brain tissue lysate with LRRTM3 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-LRRTM3 antibody
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
Product Categories/Family for anti-LRRTM3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,267 Da
NCBI Official Full Name
leucine-rich repeat transmembrane neuronal protein 3
NCBI Official Synonym Full Names
leucine rich repeat transmembrane neuronal 3
NCBI Official Symbol
LRRTM3
NCBI Protein Information
leucine-rich repeat transmembrane neuronal protein 3
UniProt Protein Name
Leucine-rich repeat transmembrane neuronal protein 3
UniProt Gene Name
LRRTM3
UniProt Entry Name
LRRT3_HUMAN
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Product Notes
The LRRTM3 lrrtm3 (Catalog #AAA302374) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRRTM3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LRRTM3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the LRRTM3 lrrtm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRTM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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