WB (Western Blot)
(Mouse CD31 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the MouseCD31 antibody detected the MouseCD31 protein (arrow).)
Rabbit M CD31 Polyclonal Antibody | anti-Pecam1 antibody
M CD31 Antibody (C-term)
Gene Names
Pecam1; Cd31; Pecam; C85791; PECAM-1
Reactivity
Mouse, Hamster
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
M CD31, Antibody; M CD31 Antibody (C-term); Platelet endothelial cell adhesion molecule; PECAM-1; CD31; Pecam1; Pecam; Pecam-1; anti-Pecam1 antibody
Host
Rabbit
Reactivity
Mouse, Hamster
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse CD31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of mouse CD31.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
508-536
Sequence Length
626
Applicable Applications for anti-Pecam1 antibody
ELISA, WB (Western Blot)
Cellular Location
Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction note= Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.
Tissue Location
Isoform 1 and isoform 3 are expressed in lung and platelets.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Mouse CD31 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the MouseCD31 antibody detected the MouseCD31 protein (arrow).)
WB (Western Blot)
(Mouse CD31 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the MouseCD31 antibody detected the MouseCD31 protein (arrow).)
WB (Western Blot)
(Mouse CD31 Antibody (C-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the MouseCD31 antibody detected the Mouse CD31 protein (arrow).)
WB (Western Blot)
(Mouse CD31 Antibody (C-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the MouseCD31 antibody detected the Mouse CD31 protein (arrow).)
Related Product Information for anti-Pecam1 antibody
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Modulates BDKRB2 activation (By similarity). Induces susceptibility to atherosclerosis.
Product Categories/Family for anti-Pecam1 antibody
References
DeLisser, H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18616-18621(2010)
Zhang, C., et al. Dev. Dyn. 239(10):2594-2602(2010)
Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010)
Ni, A., et al. Dev. Dyn. 239(9):2354-2366(2010)
Sessa, A., et al. Genes Dev. 24(16):1816-1826(2010)
Zhang, C., et al. Dev. Dyn. 239(10):2594-2602(2010)
Enciso, J.M., et al. Dev. Dyn. 239(10):2570-2583(2010)
Ni, A., et al. Dev. Dyn. 239(9):2354-2366(2010)
Sessa, A., et al. Genes Dev. 24(16):1816-1826(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
platelet endothelial cell adhesion molecule isoform 2
NCBI Official Synonym Full Names
platelet/endothelial cell adhesion molecule 1
NCBI Official Symbol
Pecam1
NCBI Official Synonym Symbols
Cd31; Pecam; C85791; PECAM-1
NCBI Protein Information
platelet endothelial cell adhesion molecule
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Gene Name
Pecam1
UniProt Synonym Gene Names
Pecam; Pecam-1; PECAM-1
UniProt Entry Name
PECA1_MOUSE
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Product Notes
The Pecam1 pecam1 (Catalog #AAA289614) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 508-536. The M CD31 Antibody (C-term) reacts with Mouse, Hamster and may cross-react with other species as described in the data sheet. AAA Biotech's M CD31 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the Pecam1 pecam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M CD31, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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