IF (Immunofluorescence)
(Confocal immunofluorescent analysis of M6PR Antibody (C-term)(AAA286592) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
Rabbit M6PR Polyclonal Antibody | anti-M6PR antibody
M6PR Antibody (C-term)
Gene Names
M6PR; SMPR; MPR46; CD-MPR; MPR 46; MPR-46
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
ELISA, Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
M6PR, Antibody; M6PR Antibody (C-term); Cation-dependent mannose-6-phosphate receptor; CD Man-6-P receptor; CD-MPR; 46 kDa mannose 6-phosphate receptor; MPR 46; M6PR; MPR46; MPRD; anti-M6PR antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human M6PR.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
230-260
Sequence Length
277
Applicable Applications for anti-M6PR antibody
ELISA, WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of M6PR Antibody (C-term)(AAA286592) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of M6PR Antibody (C-term)(AAA286592) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
FCM/FACS (Flow Cytometry)
(M6PR Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(M6PR Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(M6PR Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the M6PR antibody detected the M6PR protein (arrow).)
WB (Western Blot)
(M6PR Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the M6PR antibody detected the M6PR protein (arrow).)
Related Product Information for anti-M6PR antibody
The protein encoded by this gene is a receptor for
mannose-6-phosphate groups on lysosomal enzymes. The receptor forms
a homodimer or homotetramer for intracellular targeting of
lysosomal enzymes and export of newly synthesized lysosomal enzymes
into the cell secretions. The receptor is an integral membrane
protein which localizes to the trans-Golgi reticulum, endosomes,
and the plasma membrane.
mannose-6-phosphate groups on lysosomal enzymes. The receptor forms
a homodimer or homotetramer for intracellular targeting of
lysosomal enzymes and export of newly synthesized lysosomal enzymes
into the cell secretions. The receptor is an integral membrane
protein which localizes to the trans-Golgi reticulum, endosomes,
and the plasma membrane.
Product Categories/Family for anti-M6PR antibody
References
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
Op den Brouw, M.L., et al. Virology 393(1):84-90(2009)
Schimanski, L.M., et al. Blood Cells Mol. Dis. 43(2):180-193(2009)
Rodriguez-Gabin, A.G., et al. Exp. Cell Res. 315(13):2215-2230(2009)
Xaplanteri, P., et al. Eur. J. Immunol. 39(3):730-740(2009)
Op den Brouw, M.L., et al. Virology 393(1):84-90(2009)
Schimanski, L.M., et al. Blood Cells Mol. Dis. 43(2):180-193(2009)
Rodriguez-Gabin, A.G., et al. Exp. Cell Res. 315(13):2215-2230(2009)
Xaplanteri, P., et al. Eur. J. Immunol. 39(3):730-740(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30993
NCBI Official Full Name
cation-dependent mannose-6-phosphate receptor isoform 1
NCBI Official Synonym Full Names
mannose-6-phosphate receptor (cation dependent)
NCBI Official Symbol
M6PR
NCBI Official Synonym Symbols
SMPR; MPR46; CD-MPR; MPR 46; MPR-46
NCBI Protein Information
cation-dependent mannose-6-phosphate receptor
UniProt Protein Name
Cation-dependent mannose-6-phosphate receptor
UniProt Gene Name
M6PR
UniProt Synonym Gene Names
MPR46; MPRD; CD Man-6-P receptor; CD-MPR; MPR 46
UniProt Entry Name
MPRD_HUMAN
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Product Notes
The M6PR m6pr (Catalog #AAA286592) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 230-260. The M6PR Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's M6PR can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the M6PR m6pr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M6PR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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