IHC (Immunohiostchemistry)
(AAA329150 at 1/100 staining Rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.)
Rabbit MAML2 Polyclonal Antibody | anti-MAML2 antibody
MAML2 Antibody
Gene Names
MAML2; MAM2; MAM3; MAM-3; MLL-MAML2
Reactivity
Human, RatPredicted Reactivity: Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(88%)
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
MAML2, Antibody; MAML2 Antibody; KIAA1819; Mam 2; Mam-2; MAML2; MAML2_HUMAN; Mastermind-like protein 2; anti-MAML2 antibody
Host
Rabbit
Reactivity
Human, Rat
Predicted Reactivity: Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(88%)
Predicted Reactivity: Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(88%)
Clonality
Polyclonal
Isotype
IgG
Specificity
MAML2 Antibody detects endogenous levels of total MAML2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1mg/ml (varies by lot)
Sequence Length
1156
Applicable Applications for anti-MAML2 antibody
ELISA
Immunogen
A synthesized peptide derived from human MAML2, corresponding to a region within C-terminal amino acids.
Fragment
Fab fragment
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
IHC (Immunohiostchemistry)
(AAA329150 at 1/100 staining Rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.)
IHC (Immunohiostchemistry)
(AAA329150 at 1/100 staining Rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.)
WB (Western Blot)
(Western blot analysis of extracts from Human Breast Carcinoma, using MAML2 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Human Breast Carcinoma, using MAML2 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-MAML2 antibody
Function: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
Subcellular Location: Nucleus speckle. Note: Nuclear, in a punctate manner.
Tissue Specificity: Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle.
Subunit Structure: Interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. Forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa.
Similarity: The C-terminal domain is required for transcriptional activation.Belongs to the mastermind family.
Subcellular Location: Nucleus speckle. Note: Nuclear, in a punctate manner.
Tissue Specificity: Widely expressed with high levels detected in placenta, salivary gland and skeletal muscle.
Subunit Structure: Interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. Forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa.
Similarity: The C-terminal domain is required for transcriptional activation.Belongs to the mastermind family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed Molecular Weight: (Observed)125kD.
Predicted Molecular Weight: (Calculated)125kDa.
Predicted Molecular Weight: (Calculated)125kDa.
NCBI Official Full Name
mastermind-like protein 2
NCBI Official Synonym Full Names
mastermind like transcriptional coactivator 2
NCBI Official Symbol
MAML2
NCBI Official Synonym Symbols
MAM2; MAM3; MAM-3; MLL-MAML2
NCBI Protein Information
mastermind-like protein 2
UniProt Protein Name
Mastermind-like protein 2
UniProt Gene Name
MAML2
UniProt Synonym Gene Names
KIAA1819
UniProt Entry Name
MAML2_HUMAN
Similar Products
Product Notes
The MAML2 maml2 (Catalog #AAA329150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MAML2 Antibody reacts with Human, Rat Predicted Reactivity: Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(88%) and may cross-react with other species as described in the data sheet. AAA Biotech's MAML2 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the MAML2 maml2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAML2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.