WB (Western Blot)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, Western blottingAll lanes: Anti Mannose 6 Phosphate Receptor (Cation independent) (AAA45716) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugLane 3: 22RV1 Whole Cell Lysate at 40ugLane 4: 293T Whole Cell Lysate at 40ugPredicted bind size: 274KDObserved bind size: 274KD)
Rabbit Mannose 6 Phosphate Receptor(Cation independent) Polyclonal Antibody | anti-IGF2R antibody
Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody
Gene Names
IGF2R; MPR1; MPRI; CD222; CIMPR; M6P-R
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Mannose 6 Phosphate Receptor(Cation independent), Antibody; Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody; Cation-independent mannose-6-phosphate receptor; insulin-like growth factor 2 receptor; 300 kDa mannose 6 phosphate receptor antibody; 300 kDa mannose 6-phosphate receptor antibody; Cation independent mannose 6 phosphate receptor antibody; Cation-independent mannose-6-phosphate receptor antibody; CD222 antibody; CD222 antigen antibody; CI Man 6 P receptor antibody; CI Man-6-P receptor antibody; CI MPR antibody; CI-MPR antibody; CIMPR antibody; IGF 2 receptor antibody; IGF 2R antibody; IGF II receptor antibody; IGF-II receptor antibody; IGF2 receptor antibody; IGF2R antibody; Insulin like growth factor 2 receptor antibody; Insulin like growth factor II receptor antibody; Insulin-like growth factor 2 receptor antibody; Insulin-like growth factor II receptor antibody; M6P R antibody; M6P/IGF2 receptor antibody; M6P/IGF2R antibody; M6PR antibody; MPR 300 antibody; MPR300 antibody; MPRI antibody; MPRI_HUMAN antibody; anti-IGF2R antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
2491
Applicable Applications for anti-IGF2R antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor (Cation independent) (2475-2491aa TKLVSFHDDSDEDLLHI), different from the related rat and mouse sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, Western blottingAll lanes: Anti Mannose 6 Phosphate Receptor (Cation independent) (AAA45716) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugLane 3: 22RV1 Whole Cell Lysate at 40ugLane 4: 293T Whole Cell Lysate at 40ugPredicted bind size: 274KDObserved bind size: 274KD)
WB (Western Blot)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, Western blottingAll lanes: Anti Mannose 6 Phosphate Receptor (Cation independent) (AAA45716) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugLane 3: 22RV1 Whole Cell Lysate at 40ugLane 4: 293T Whole Cell Lysate at 40ugPredicted bind size: 274KDObserved bind size: 274KD)
ICC (Immunocytochemistry)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, AAA45716, ICCICC: HCT116 Cell)
ICC (Immunocytochemistry)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, AAA45716, ICCICC: HCT116 Cell)
IHC (Immunohistochemistry)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, AAA45716, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody, AAA45716, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
Related Product Information for anti-IGF2R antibody
Description: Rabbit IgG polyclonal antibody for Cation-independent mannose-6-phosphate receptor(IGF2R) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.
Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
274,375 Da
NCBI Official Full Name
Cation-independent mannose-6-phosphate receptor
NCBI Official Synonym Full Names
insulin-like growth factor 2 receptor
NCBI Official Symbol
IGF2R
NCBI Official Synonym Symbols
MPR1; MPRI; CD222; CIMPR; M6P-R
NCBI Protein Information
cation-independent mannose-6-phosphate receptor; M6PR; CI-MPR; MPR 300; M6P/IGF2R; IGF-II receptor; M6P/IGF2 receptor; CI Man-6-P receptor; 300 kDa mannose 6-phosphate receptor; insulin-like growth factor II receptor; cation-independent mannose-6 phosphate receptor
UniProt Protein Name
Cation-independent mannose-6-phosphate receptor
UniProt Gene Name
IGF2R
UniProt Synonym Gene Names
MPRI; CI Man-6-P receptor; CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R
UniProt Entry Name
MPRI_HUMAN
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Product Notes
The IGF2R igf2r (Catalog #AAA45716) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mannose 6 Phosphate Receptor(Cation independent) antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Mannose 6 Phosphate Receptor(Cation independent) can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the IGF2R igf2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mannose 6 Phosphate Receptor(Cation independent), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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