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product-image-AAA107748_WB13.jpg WB (Western Blot) (Western blot of HeLa celllysates that had been treated with UV or untreated (Control) showing specific immunolabeling of ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182)

Rabbit MAPK14 Polyclonal Antibody | anti-MAPK14 antibody

MAPK14 antibody (Thr180/Tyr182)

Gene Names
MAPK14; RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA
Applications
Immunohistochemistry, Western Blot
Purity
MAPK14 antibody was purified by affinity chromatography
Synonyms
MAPK14, Antibody; MAPK14 antibody (Thr180/Tyr182); Polyclonal MAPK14; Anti-MAPK14; MAPK 14; MAPK-14; MAPK14; CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase p38 alpha; MAX interacting protein 2; MAX-interacting protein 2; Mitogen Activated Protein Kinase 14; Mitogen activated protein kinase p38 alpha; Mitogen-activated protein kinase 14; Mitogen-activated protein kinase p38 alpha; Mxi 2; Mxi2; p38 ALPHA; p38 MAP kinase; p38 MAPK; p38 mitogen activated protein kinase; p38ALPHA; p38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress Activated Protein Kinase 2A; anti-MAPK14 antibody
Ordering
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
MAPK14 antibody was purified by affinity chromatography
Form/Format
Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol
Sequence Length
360
Applicable Applications for anti-MAPK14 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Biological Significance
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

WB (Western Blot)

(Western blot of HeLa celllysates that had been treated with UV or untreated (Control) showing specific immunolabeling of ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182)

product-image-AAA107748_WB13.jpg WB (Western Blot) (Western blot of HeLa celllysates that had been treated with UV or untreated (Control) showing specific immunolabeling of ~39k p38 MAPK protein phosphorylated at Thr180/Tyr182)

IHC (Immunohistochemistry)

(Immunohistochemical staining of human breast cancer tissue showing p38 when phosphorylatedat Thr180/Tyr182 in red.)

product-image-AAA107748_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemical staining of human breast cancer tissue showing p38 when phosphorylatedat Thr180/Tyr182 in red.)
Related Product Information for anti-MAPK14 antibody
Rabbit polyclonal MAPK14 antibody (Thr180/Tyr182)
Product Categories/Family for anti-MAPK14 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
29,388 Da
NCBI Official Full Name
MAPK14
NCBI Official Synonym Full Names
mitogen-activated protein kinase 14
NCBI Official Symbol
MAPK14
NCBI Official Synonym Symbols
RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA
NCBI Protein Information
mitogen-activated protein kinase 14
UniProt Protein Name
Mitogen-activated protein kinase 14
UniProt Gene Name
MAPK14
UniProt Synonym Gene Names
CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; MAP kinase 14; MAPK 14; CSAID-binding protein; CSBP; MAP kinase p38 alpha; SAPK2a
UniProt Entry Name
MK14_HUMAN

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Product Notes

The MAPK14 mapk14 (Catalog #AAA107748) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MAPK14 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MAPK14 mapk14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPK14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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