Rabbit MAPKBP1 Polyclonal Antibody | anti-MAPKBP1 antibody

MAPKBP1 Polyclonal Antibody

Cat. Num. AAA10759

• Gene Names: MAPKBP1; JNKBP-1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purification
• Synonyms: MAPKBP1; Polyclonal Antibody; MAPKBP1 Polyclonal Antibody; JNKBP-1; JNKBP1; NPHP20; anti-MAPKBP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
• Sequence Length: 1514

• Applicable Applications for anti-MAPKBP1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500 - 2000; IHC: 1:50 - 1:100
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1).
• Category: Primary antibody
• Preparation and Storage: Store at -20 degree C. Avoid freeze / thaw cycles.

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human stomach using MAPKBP1 antibody at dilution of 1:100 (40x lens).)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded mouse stomach using MAPKBP1 antibody (AAA10759) at dilution of 1:100 (40x lens).)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using MAPKBP1 antibody (AAA10759) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 60s.)

Related Product Information for anti-MAPKBP1 antibody

This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.

Product Categories/Family for anti-MAPKBP1 antibody

Polyclonal

NCBI and Uniprot Product Information

• NCBI GI #: 215274254
• NCBI GeneID: 23005
• UniProt Accession #: O60336; Q14CB5; Q14CD8; Q49AJ8; Q5W9G9; A6NM93; A8K8P9
• Molecular Weight: Observed MW: 164kDa; Calculated MW: 23kDa/109kDa/134kDa/149kDa/163kDa
• NCBI Official Full Name: Mitogen-activated protein kinase-binding protein 1
• NCBI Official Synonym Full Names: mitogen-activated protein kinase binding protein 1
• NCBI Official Symbol: MAPKBP1
• NCBI Official Synonym Symbols: JNKBP-1
• NCBI Protein Information: mitogen-activated protein kinase-binding protein 1; JNK-binding protein 1; mitogen activated protein kinase binding protein 1
• UniProt Protein Name: Mitogen-activated protein kinase-binding protein 1
• UniProt Gene Name: MAPKBP1
• UniProt Synonym Gene Names: JNKBP1; KIAA0596; JNKBP-1
• UniProt Entry Name: MABP1_HUMAN