IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin- embedded human-brain, antibody was diluted at 1:100.)
Rabbit anti-Human, Rat MDK Polyclonal Antibody | anti-MDK antibody
MDK Antibody
Gene Names
MDK; MK; ARAP; NEGF2
Reactivity
Human, Rat
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
MDK, Antibody; MDK Antibody; MDK; FLJ27379; MK; NEGF2; anti-MDK antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MK Polyclonal Antibody detects endogenous levels of MK protein.
Purity/Purification
Affinity purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Sequence Length
143
Applicable Applications for anti-MDK antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Conjugation
APC
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MDK. AA range:94-143
Organism
Human,Rat
Cellular Localization
Secreted.
Tissue specificity
Expressed in various tumor cell lines. In insulinoma tissue predominantly expressed in precancerous lesions.
Function
Function:Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.,induction:By heparin and retinoic acid.,similarity:Belongs to the pleiotrophin family.,subunit:Homodimer.
Preparation and Storage
Store at -15 degree C to -25 degree C / 1 year (Do not lower than -25 degree C)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin- embedded human-brain, antibody was diluted at 1:100.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin- embedded human-brain, antibody was diluted at 1:100.)
WB (Western Blot)
(Western blot analysis of lysate from SW480 cells, using MDK Antibody.)
WB (Western Blot)
(Western blot analysis of lysate from SW480 cells, using MDK Antibody.)
WB (Western Blot)
(Western blot analysis of extracts of SW480 cells, using MDK antibody.)
WB (Western Blot)
(Western blot analysis of extracts of SW480 cells, using MDK antibody.)
Related Product Information for anti-MDK antibody
Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MK is a non-glycosylated protein that shows greater than 87% identity between human and mouse. The carboxy-terminus of MK contains the principle heparin-binding site and the molecule's neurite-promoting sequences; both the amino-and carboxy-terminal sequences are required for the molecule's neurotrophic properties. An association between overexpression of MK and colon adenocarcinoma has been shown in families suffering from familial polyposis. In addition, MK functions to enhance the activity of plasminogen activator (PA).
Product Categories/Family for anti-MDK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18kD (Observed)
NCBI Official Full Name
midkine isoform a
NCBI Official Synonym Full Names
midkine
NCBI Official Symbol
MDK
NCBI Official Synonym Symbols
MK; ARAP; NEGF2
NCBI Protein Information
midkine
UniProt Protein Name
Midkine
UniProt Gene Name
MDK
UniProt Synonym Gene Names
MK1; NEGF2; MK; ARAP
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Product Notes
The MDK mdk (Catalog #AAA267052) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MDK Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MDK can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MDK mdk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MDK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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