Rabbit anti-Human, Mouse MX1 Polyclonal Antibody | anti-MX1 antibody

MX1 Antibody

Cat. Num. AAA232594

• Gene Names: MX1; MX; MxA; IFI78; IFI-78K
• Reactivity: Human, Mouse
• Applications: Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: >95%, Protein G purified
• Synonyms: MX1, Antibody; MX1 Antibody; Interferon-induced GTP-binding protein Mx1; Interferon-induced protein p78; IFI-78K; Interferon-regulated resistance GTP-binding protein MxA; Myxoma resistance pr; MX1; anti-MX1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 662

• Applicable Applications for anti-MX1 antibody: IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Immunogen: Recombinant Human Interferon-induced GTP-binding protein Mx1 protein (7-172AA)
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Immunogen Species: Homo sapines (Human)
• Research Area: Microbiology
• Target Names: MX1
• Preparation and Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

IP (Immunoprecipitation)

(Immunoprecipitating MX1 in Hela whole cell lysateLane 1: Rabbit monoclonal IgG(1ug)instead of AAA232594 in Hela whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)Lane 2: AAA232594(4ug)+ Hela whole cell lysate(500ug)Lane 3: Hela whole cell lysate (20ug))

IF (Immunofluorescence)

(Immunofluorescent analysis of PC3 cells using AAA232594 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human testicular tissue using AAA232594 at dilution of 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA232594 at dilution of 1:100)

WB (Western Blot)

(Western BlotPositive WB detected in:A549 whole cell lysate,NIH/3T3 whole cell lysate,Hela whole cell lysateAll lanes: MX1 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 76,56 kDaObserved band size: 76 kDa)

Related Product Information for anti-MX1 antibody

Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

NCBI and Uniprot Product Information

• NCBI GI #: 222136619
• NCBI GeneID: 4599
• NCBI Accession #: NP_001138397.1
• NCBI GenBank Nucleotide #: NM_001144925.2
• UniProt Accession #: P20591; Q86YP5; Q96CI3; B2RDA5; B3KU10; C9IYV7; C9J8D6; C9JN19; C9JN88; C9JUL1; C9JZS6; D3DSI8
• NCBI Official Full Name: interferon-induced GTP-binding protein Mx1 isoform a
• NCBI Official Synonym Full Names: MX dynamin like GTPase 1
• NCBI Official Symbol: MX1
• NCBI Official Synonym Symbols: MX; MxA; IFI78; IFI-78K
• NCBI Protein Information: interferon-induced GTP-binding protein Mx1
• UniProt Protein Name: Interferon-induced GTP-binding protein Mx1
• UniProt Gene Name: MX1
• UniProt Synonym Gene Names: IFI-78K
• UniProt Entry Name: MX1_HUMAN