IHC (Immunohiostchemistry)
(Anti- Neuropillin-1 Picoband antibody, AAA46527, IHC(P)IHC(P): Human Placenta Tissue)
anti-Human, Rat Neuropilin 1 Polyclonal Antibody | anti-NRP1 antibody
Anti-Neuropilin 1 Antibody
Gene Names
NRP1; NP1; NRP; BDCA4; CD304; VEGF165R
Reactivity
Human, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
Neuropilin 1, Antibody; Anti-Neuropilin 1 Antibody; Neuropilin-1; A5 protein; BDCA4; BLOOD DENDRITIC CELL ANTIGEN 4; CD 304; CD304; DKFZp686A03134; DKFZp781F1414; Neuropilin1; Neuropilin1 transmembrane receptor; NP1; NPN1; NRP 1; NRP; NRP1; NRP1_HUMAN; Vascular endothelial cell growth factor 165 receptor; VEGF165R; neuropilin 1; anti-NRP1 antibody
Reactivity
Human, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
644
Applicable Applications for anti-NRP1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti- Neuropillin-1 Picoband antibody, AAA46527, IHC(P)IHC(P): Human Placenta Tissue)
IHC (Immunohiostchemistry)
(Anti- Neuropillin-1 Picoband antibody, AAA46527, IHC(P)IHC(P): Human Placenta Tissue)
WB (Western Blot)
(Anti- Neuropillin-1 Picoband antibody, AAA46527, Western blottingAll lanes: Anti Neuropillin-1 (AAA46527) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: Human Placenta Tissue Lysate at 50ugLane 4: Rat Cardiac Muscle Tissue Lysate at 50ugPredicted bind size: 103KDObserved bind size: 103KD)
WB (Western Blot)
(Anti- Neuropillin-1 Picoband antibody, AAA46527, Western blottingAll lanes: Anti Neuropillin-1 (AAA46527) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: Human Placenta Tissue Lysate at 50ugLane 4: Rat Cardiac Muscle Tissue Lysate at 50ugPredicted bind size: 103KDObserved bind size: 103KD)
Related Product Information for anti-NRP1 antibody
Description: Rabbit IgG polyclonal antibody for Neuropilin-1(NRP1) detection. Tested with WB, IHC-P in Human;Rat.
Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
References
1. Gagnon, M. L., Bielenberg, D. R., Gechtman, Z., Miao, H.-Q., Takashima, S., Soker, S., Klagsbrun, M. Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: in vivo expression and antitumor activity. Proc. Nat. Acad. Sci. 97: 2573-2578, 2000. 2. Gu, C., Rodriguez, E. R., Riemert, D. V., Shu, T., Fritzsch, B., Richards, L. J., Kolodkin, A. L., Ginty, D. D. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev. Cell 5: 45-57, 2003.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
neuropilin-1 isoform b
NCBI Official Synonym Full Names
neuropilin 1
NCBI Official Symbol
NRP1
NCBI Official Synonym Symbols
NP1; NRP; BDCA4; CD304; VEGF165R
NCBI Protein Information
neuropilin-1
UniProt Protein Name
Neuropilin-1
UniProt Gene Name
NRP1
UniProt Synonym Gene Names
NRP; VEGF165R
UniProt Entry Name
NRP1_HUMAN
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Product Notes
The NRP1 nrp1 (Catalog #AAA46527) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Neuropilin 1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Neuropilin 1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NRP1 nrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuropilin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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