IHC (Immunohistochemisry)
(NR0B1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NR0B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human NR0B1 Polyclonal Antibody | anti-NR0B1 antibody
NR0B1 Antibody (Center)
Gene Names
NR0B1; AHC; AHX; DSS; GTD; HHG; AHCH; DAX1; DAX-1; NROB1; SRXY2
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
NR0B1, Antibody; NR0B1 Antibody (Center); Nuclear receptor subfamily 0 group B member 1; DSS-AHC critical region on the X chromosome protein 1; Nuclear receptor DAX-1; NR0B1; AHC; DAX1; anti-NR0B1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This NR0B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human NR0B1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.37 (varies by lot)
Sequence Positions
304-333
Sequence Length
400
Applicable Applications for anti-NR0B1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(NR0B1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NR0B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(NR0B1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NR0B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of NR0B1 (arrow) using rabbit polyclonal NR0B1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NR0B1 gene.)
WB (Western Blot)
(Western blot analysis of NR0B1 (arrow) using rabbit polyclonal NR0B1 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NR0B1 gene.)
WB (Western Blot)
(NR0B1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NR0B1 antibody detected the NR0B1 protein (arrow).)
WB (Western Blot)
(NR0B1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NR0B1 antibody detected the NR0B1 protein (arrow).)
Related Product Information for anti-NR0B1 antibody
This gene encodes a protein that contains a DNA-binding
domain. The encoded protein acts as a dominant-negative regulator
of transcription which is mediated by the retinoic acid receptor.
This protein also functions as an anti-testis gene by acting
antagonistically to Sry. Mutations in this gene result in both
X-linked congenital adrenal hypoplasia and hypogonadotropic
hypogonadism.
domain. The encoded protein acts as a dominant-negative regulator
of transcription which is mediated by the retinoic acid receptor.
This protein also functions as an anti-testis gene by acting
antagonistically to Sry. Mutations in this gene result in both
X-linked congenital adrenal hypoplasia and hypogonadotropic
hypogonadism.
Product Categories/Family for anti-NR0B1 antibody
References
Li, N., et al. J. Clin. Endocrinol. Metab. 95 (9), E104-E111 (2010) :
Nedumaran, B., et al. J. Biol. Chem. 285(12):9221-9232(2010)
Kinsey, M., et al. Cancer Res. 69(23):9047-9055(2009)
Nagl, F., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1146-C1156 (2009) :
Skinningsrud, B., et al. J. Clin. Endocrinol. Metab. 94(10):4086-4093(2009)
Nedumaran, B., et al. J. Biol. Chem. 285(12):9221-9232(2010)
Kinsey, M., et al. Cancer Res. 69(23):9047-9055(2009)
Nagl, F., et al. Am. J. Physiol., Cell Physiol. 297 (5), C1146-C1156 (2009) :
Skinningsrud, B., et al. J. Clin. Endocrinol. Metab. 94(10):4086-4093(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51718
NCBI Official Full Name
nuclear receptor subfamily 0 group B member 1
NCBI Official Synonym Full Names
nuclear receptor subfamily 0, group B, member 1
NCBI Official Symbol
NR0B1
NCBI Official Synonym Symbols
AHC; AHX; DSS; GTD; HHG; AHCH; DAX1; DAX-1; NROB1; SRXY2
NCBI Protein Information
nuclear receptor subfamily 0 group B member 1
UniProt Protein Name
Nuclear receptor subfamily 0 group B member 1
UniProt Gene Name
NR0B1
UniProt Synonym Gene Names
AHC; DAX1
UniProt Entry Name
NR0B1_HUMAN
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Product Notes
The NR0B1 nr0b1 (Catalog #AAA284258) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 304-333. The NR0B1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NR0B1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the NR0B1 nr0b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NR0B1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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