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IHC (Immunohistochemistry)
(Anti-Nucleophosmin antibody, AAA45382, IHC(P)IHC(P): Rat Spleen Tissue)
Rabbit Nucleophosmin Polyclonal Antibody | anti-NPM1 antibody
Anti-Nucleophosmin antibody
Gene Names
NPM1; B23; NPM
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Nucleophosmin, Antibody; Anti-Nucleophosmin antibody; Nucleophosmin; nucleophosmin(nucleolar phosphoprotein B23, numatrin); B23 antibody; MGC104254 antibody; NO38 antibody; NPM antibody; NPM_HUMAN antibody; NPM1 antibody; Nucleolar Phosphoprotein B23 antibody; Nucleolar protein NO38 antibody; Nucleophosmin(nucleolar phosphoprotein B23 numatrin) antibody; Nucleophosmin antibody; Nucleophosmin/nucleoplasmin family member 1 antibody; Numatrin antibody; OTTHUMP00000161024 antibody; OTTHUMP00000161025 antibody; OTTHUMP00000223397 antibody; OTTHUMP00000223398 antibody; anti-NPM1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
294
Applicable Applications for anti-NPM1 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Nucleophosmin (22-41aa ELKADKDYHFKVDNDENEHQ), identical to the related rat and mouse sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti-Nucleophosmin antibody, AAA45382, IHC(P)IHC(P): Rat Spleen Tissue)
IHC (Immunohistochemistry)
(Anti-Nucleophosmin antibody, AAA45382, IHC(P)IHC(P): Rat Spleen Tissue)
ICC (Immunocytochemistry)
(Anti-Nucleophosmin antibody, AAA45382, ICCICC: HELA Cell)
ICC (Immunocytochemistry)
(Anti-Nucleophosmin antibody, AAA45382, ICCICC: HELA Cell)
IHC (Immunohiostchemistry)
(Anti-Nucleophosmin antibody, AAA45382, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Nucleophosmin antibody, AAA45382, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti-Nucleophosmin antibody, AAA45382, Western blottingLane 1: Rat Testis Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: HELA Cell LysateLane 4: U87 Cell LysateLane 5: A549 Cell LysateLane6: SMMC Cell Lysate)
WB (Western Blot)
(Anti-Nucleophosmin antibody, AAA45382, Western blottingLane 1: Rat Testis Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: HELA Cell LysateLane 4: U87 Cell LysateLane 5: A549 Cell LysateLane6: SMMC Cell Lysate)
Related Product Information for anti-NPM1 antibody
Description: Rabbit IgG polyclonal antibody for Nucleophosmin(NPM1) detection. Tested with WB, IHC-P, ICC in Human, Mouse, Rat.
Background: NPM1(Nucleophosmin/Nucleoplasmin family, member1), also known as NPM, nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. The NPM1 gene maps to chromosome 5q35. Chan et al.(1989) found that nucleophosmin is a nucleolar phosphoprotein that is more abundant in tumor cells than in normal resting cells. Stimulation of the growth of normal cells, e.g., mitogen activation of B lymphocytes, was accompanied by an increase in nucleophosmin protein level. They stated that nucleophosmin is likely involved in the assembly of ribosomal proteins into ribosomes. Electron microscopic study indicated that nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.
Background: NPM1(Nucleophosmin/Nucleoplasmin family, member1), also known as NPM, nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. The NPM1 gene maps to chromosome 5q35. Chan et al.(1989) found that nucleophosmin is a nucleolar phosphoprotein that is more abundant in tumor cells than in normal resting cells. Stimulation of the growth of normal cells, e.g., mitogen activation of B lymphocytes, was accompanied by an increase in nucleophosmin protein level. They stated that nucleophosmin is likely involved in the assembly of ribosomal proteins into ribosomes. Electron microscopic study indicated that nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
28,400 Da
NCBI Official Full Name
Nucleophosmin
NCBI Official Synonym Full Names
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NCBI Official Symbol
NPM1
NCBI Official Synonym Symbols
B23; NPM
NCBI Protein Information
nucleophosmin; nucleolar protein NO38; nucleophosmin/nucleoplasmin family, member 1
UniProt Protein Name
Nucleophosmin
UniProt Gene Name
NPM1
UniProt Synonym Gene Names
NPM; NPM
UniProt Entry Name
NPM_HUMAN
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Product Notes
The NPM1 npm1 (Catalog #AAA45382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Nucleophosmin antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nucleophosmin can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NPM1 npm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nucleophosmin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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