WB (Western Blot)
(Western Blot of 20 ug of human hippocampus tissue lysate (lanes 2 and 4) showing specific immunolabeling of Nurr1. Peptide absorption control lane 3.)
Rabbit Nurr1 Polyclonal Antibody | anti-NR4A2 antibody
Anti-Nurr1 Antibody
Gene Names
NR4A2; NOT; RNR1; HZF-3; NURR1; TINUR
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
Nurr1, Antibody; Anti-Nurr1 Antibody; NR4A2; Nuclear receptor subfamily 4 group A member 2; Immediate-early response protein NOT; Orphan nuclear receptor NURR1; Transcriptionally-inducible nuclear receptor; NOT; NURR1; TINUR; Nurr1; anti-NR4A2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Reacts with an internal sequence of the human Nurr1 protein. Also reacts with rat and mouse Nurr1.
Form/Format
Liquid; Antigen Affinity Purified; PBS + 0.02% NaN3
Applicable Applications for anti-NR4A2 antibody
WB (Western Blot)
Immunogen Species
Human
Immunogen
Synthetic peptide corresponding to amino acids from an internal sequence of the human Nurr1 protein
Country of Origin
United States
Preparation and Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20 degree C or -80 degree C, while keeping a working aliquot stored at 4 degree C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
After date of receipt, stable for at least 1 year at -20 degree C.
After date of receipt, stable for at least 1 year at -20 degree C.
WB (Western Blot)
(Western Blot of 20 ug of human hippocampus tissue lysate (lanes 2 and 4) showing specific immunolabeling of Nurr1. Peptide absorption control lane 3.)
WB (Western Blot)
(Western Blot of 20 ug of human hippocampus tissue lysate (lanes 2 and 4) showing specific immunolabeling of Nurr1. Peptide absorption control lane 3.)
IHC (Immunohistochemistry)
(Immunohistochemistry of adult rat brain hippocampus showing specific staining of Nurr1. Tissue was fixed in paraformaldehyde and cut into 20 micron sections.)
IHC (Immunohistochemistry)
(Immunohistochemistry of adult rat brain hippocampus showing specific staining of Nurr1. Tissue was fixed in paraformaldehyde and cut into 20 micron sections.)
Related Product Information for anti-NR4A2 antibody
Nurr1 rabbit polyclonal primary antibody from the lab is produced in-house. It detects human, mouse, and rat Nurr1 and is antigen affinity purified. It is great for use in WB.
The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.
The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.
Product Categories/Family for anti-NR4A2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,809 Da
NCBI Official Full Name
Homo sapiens nuclear receptor subfamily 4, group A, member 2 (NR4A2), mRNA
NCBI Official Synonym Full Names
nuclear receptor subfamily 4, group A, member 2
NCBI Official Symbol
NR4A2
NCBI Official Synonym Symbols
NOT; RNR1; HZF-3; NURR1; TINUR
NCBI Protein Information
nuclear receptor subfamily 4 group A member 2; NGFI-B/nur77 beta-type transcription factor homolog; T-cell nuclear receptor NOT; immediate-early response protein NOT; intermediate-early receptor protein; nuclear receptor related 1; nur related protein-1,
UniProt Protein Name
Nuclear receptor subfamily 4 group A member 2
UniProt Gene Name
NR4A2
UniProt Synonym Gene Names
NOT; NURR1; TINUR
UniProt Entry Name
NR4A2_HUMAN
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Product Notes
The NR4A2 nr4a2 (Catalog #AAA72776) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Nurr1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nurr1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the NR4A2 nr4a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nurr1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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