Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody recognizes human p53.
Form/Format
100ug peptide affinity-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Sequence Length
393
Applicable Applications for anti-p53 antibody
IB (Immunoblot)
Immunogen
Synthetic peptide corresponding to amino acids at the C-terminus of human p53.
Preparation and Storage
This antibody is stable for at least one (1) year at-20 degree C.
Related Product Information for anti-p53 antibody
Tumor protein p53, also known as p53, functions as a tumor suppressor, and, as such, p53 has been described as "the guardian of the genome" because of its role in preventing genome mutations. The name p53 describes the apparent molecular mass of the protein as observed in SDS-PAGE analysis. The actual mass of full-length p53, based on the sum of masses of the amino acid residues, is 43.7kDa. The difference is due to the number of proline residues in the protein which slow its migration on SDS-PAGE, thus making it appear heavier than it actually is. The TP53 gene is the most frequently mutated gene (>50%) in human cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,826 Da
NCBI Official Full Name
cellular tumor antigen p53 isoform a
NCBI Official Synonym Full Names
tumor protein p53
NCBI Official Symbol
TP53
NCBI Official Synonym Symbols
P53; BCC7; LFS1; TRP53
NCBI Protein Information
cellular tumor antigen p53
UniProt Protein Name
Cellular tumor antigen p53
UniProt Gene Name
TP53
UniProt Synonym Gene Names
P53
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Product Notes
The p53 tp53 (Catalog #AAA47853) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's p53 can be used in a range of immunoassay formats including, but not limited to, IB (Immunoblot). Researchers should empirically determine the suitability of the p53 tp53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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