IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using PARN antibody.)
Rabbit anti-Human PARN Polyclonal Antibody | anti-PARN antibody
PARN Polyclonal Antibody
Gene Names
PARN; DAN; DKCB6; PFBMFT4
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
PARN, Antibody; PARN Polyclonal Antibody; DAN; Deadenylating nuclease; Deadenylation nuclease; PARN; Poly A specific ribonuclease; Poly(A) specific ribonuclease; Poly(A)-specific ribonuclease PARN; Polyadenylate specific ribonuclease; Polyadenylate-specific ribonuclease; anti-PARN antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
578
Applicable Applications for anti-PARN antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human PARN
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using PARN antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using PARN antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human esophageal cancer using PARN antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human esophageal cancer using PARN antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using PARN antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using PARN antibody.)
Related Product Information for anti-PARN antibody
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-PARN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 52kDa; 66kDa; 67kDa; 73kDa
Observed: 75kDa
Observed: 75kDa
NCBI Official Full Name
poly(A)-specific ribonuclease PARN isoform 2
NCBI Official Synonym Full Names
poly(A)-specific ribonuclease
NCBI Official Symbol
PARN
NCBI Official Synonym Symbols
DAN; DKCB6; PFBMFT4
NCBI Protein Information
poly(A)-specific ribonuclease PARN
UniProt Protein Name
Poly(A)-specific ribonuclease PARN
UniProt Gene Name
PARN
UniProt Synonym Gene Names
DAN
Similar Products
Product Notes
The PARN parn (Catalog #AAA174340) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARN Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PARN can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PARN parn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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