IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with SNK Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit PLK2 (SNK) Polyclonal Antibody | anti-PLK2 antibody
PLK2 (SNK) Antibody (C-term)
Gene Names
PLK2; SNK; hSNK; hPlk2
Reactivity
Human, mouse, rat
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PLK2 (SNK), Antibody; PLK2 (SNK) Antibody (C-term); Serine/threonine-protein kinase PLK2; Polo-like kinase 2; PLK-2; hPlk2; Serine/threonine-protein kinase SNK; hSNK; Serum-inducible kinase; PLK2; SNK; anti-PLK2 antibody
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PLK2 (SNK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-406 amino acids from the C-terminal region of human PLK2 (SNK).
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
375-406
Sequence Length
685
Applicable Applications for anti-PLK2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with SNK Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with SNK Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(The anti-SNK C-term Pab is used in Western blot to detect SNK in PMA-treated Pam212 cell lysate (lane 1) and rat testis tissue lysate (lane 2).)
WB (Western Blot)
(The anti-SNK C-term Pab is used in Western blot to detect SNK in PMA-treated Pam212 cell lysate (lane 1) and rat testis tissue lysate (lane 2).)
Related Product Information for anti-PLK2 antibody
Plks (polo-like kinases) encode serine/threonine kinases that are closely
related to polo and CDC5, genes that are required for passage through mitosis
in Drosophila and Saccharomyces, respectively. Polo-like kinases, which
include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk
(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell
proliferation. Plk protein accumulates in the cell during S and G2 phases of
the cell cycle, and both protein content and catalytic activity peak at the
onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are
immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
related to polo and CDC5, genes that are required for passage through mitosis
in Drosophila and Saccharomyces, respectively. Polo-like kinases, which
include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk
(for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell
proliferation. Plk protein accumulates in the cell during S and G2 phases of
the cell cycle, and both protein content and catalytic activity peak at the
onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are
immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
Product Categories/Family for anti-PLK2 antibody
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Liby, K., et al., DNA Seq. 11:527-533 (2001).
Liby, K., et al., DNA Seq. 11:527-533 (2001).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78237
NCBI Official Full Name
serine/threonine-protein kinase PLK2 isoform 2
NCBI Official Synonym Full Names
polo-like kinase 2
NCBI Official Symbol
PLK2
NCBI Official Synonym Symbols
SNK; hSNK; hPlk2
NCBI Protein Information
serine/threonine-protein kinase PLK2
UniProt Protein Name
Serine/threonine-protein kinase PLK2
UniProt Gene Name
PLK2
UniProt Synonym Gene Names
SNK; PLK-2; hPlk2; hSNK
UniProt Entry Name
PLK2_HUMAN
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Product Notes
The PLK2 plk2 (Catalog #AAA287382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 375-406. The PLK2 (SNK) Antibody (C-term) reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLK2 (SNK) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PLK2 plk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLK2 (SNK), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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