IHC (Immunohistochemisry)
(Anti-PP2A-alpha antibody, AAA45138, IHC(P)IHC(P): Rat Kidney Tissue)
Rabbit PP2A Polyclonal Antibody | anti-PPP2CA antibody
Anti-PP2A antibody
Gene Names
PPP2CA; RP-C; PP2Ac; PP2CA; PP2Calpha
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
PP2A, Antibody; Anti-PP2A antibody; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PP2A-alpha); protein phosphatase 2, catalytic subunit, alpha isozyme; PP2A alpha antibody; PP2A-alpha antibody; PP2AA_HUMAN antibody; PP2Aalpha antibody; PP2Ac antibody; PP2CA antibody; PP2Calpha antibody; PPP2CA antibody; Protein phosphatase 2(formerly 2A) catalytic subunit alpha isoform antibody; Protein phosphatase 2 catalytic subunit alpha isoform antibody; Protein phosphatase 2, catalytic subunit, alpha isozyme antibody; Protein phosphatase 2A catalytic subunit, alpha isoform antibody; Replication protein C antibody; RP C antibody; RP-C antibody; RPC antibody; Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody; anti-PPP2CA antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
309
Applicable Applications for anti-PPP2CA antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A (6-20aa FTKELDQWIEQLNEC), identical to the related rat and mouse sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti-PP2A-alpha antibody, AAA45138, IHC(P)IHC(P): Rat Kidney Tissue)
IHC (Immunohistochemisry)
(Anti-PP2A-alpha antibody, AAA45138, IHC(P)IHC(P): Rat Kidney Tissue)
IHC (Immunohiostchemistry)
(Anti-PP2A-alpha antibody, AAA45138, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-PP2A-alpha antibody, AAA45138, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-PP2A-alpha antibody, AAA45138, Western blottingAll lanes: Anti PP2A-alpha(AAA45138) at 0.5ug/mlLane 1: Rat kidney Tissue Lysate at 50ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD)
WB (Western Blot)
(Anti-PP2A-alpha antibody, AAA45138, Western blottingAll lanes: Anti PP2A-alpha(AAA45138) at 0.5ug/mlLane 1: Rat kidney Tissue Lysate at 50ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD)
Related Product Information for anti-PPP2CA antibody
Description: Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PPP2CA) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: The catalytic subunit of human protein phosphatase 2A(PPP2CA) encodes a 309-amino acid polypeptide.It is localized to chromosome 5. The gene(approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue(Leu309) of protein serine/threonine phosphatase 2A catalytic subunit(PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
Background: The catalytic subunit of human protein phosphatase 2A(PPP2CA) encodes a 309-amino acid polypeptide.It is localized to chromosome 5. The gene(approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue(Leu309) of protein serine/threonine phosphatase 2A catalytic subunit(PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
29,735 Da
NCBI Official Full Name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
NCBI Official Synonym Full Names
protein phosphatase 2, catalytic subunit, alpha isozyme
NCBI Official Symbol
PPP2CA
NCBI Official Synonym Symbols
RP-C; PP2Ac; PP2CA; PP2Calpha
NCBI Protein Information
serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; replication protein C; protein phosphatase 2A catalytic subunit, alpha isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform
UniProt Protein Name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
UniProt Gene Name
PPP2CA
UniProt Synonym Gene Names
PP2A-alpha; RP-C
UniProt Entry Name
PP2AA_HUMAN
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Product Notes
The PPP2CA ppp2ca (Catalog #AAA45138) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PP2A antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PP2A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PPP2CA ppp2ca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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