IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Rabbit PP5 (PP5C) Polyclonal Antibody | anti-PPP5C antibody
PP5 (PP5C) Antibody (C-term)
Gene Names
PPP5C; PP5; PPT; PPP5
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PP5 (PP5C), Antibody; PP5 (PP5C) Antibody (C-term); Serine/threonine-protein phosphatase 5; PP5; Protein phosphatase T; PP-T; PPT; PPP5C; PPP5; anti-PPP5C antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PP5 (PP5C) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-475 amino acids from the C-terminal region of human PP5 (PP5C).
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
445-475
Sequence Length
499
Applicable Applications for anti-PPP5C antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(Western blot analysis of hPPP5C-N61 in A375, A2058 cell line lysates (35ug/lane). PPP5C (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of hPPP5C-N61 in A375, A2058 cell line lysates (35ug/lane). PPP5C (arrow) was detected using the purified Pab.)
Related Product Information for anti-PPP5C antibody
PPP5C belongs to the PPP phosphatase family, PP-T subfamily, and may play a role in the regulation of RNA biogenesis and/or mitosis. In vitro,PPP5C dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1.
References
Yang, J., et al., EMBO J. 24(1):1-10 (2005).
Zhou, G., et al., J. Biol. Chem. 279(45):46595-46605 (2004).
Huang, S., et al., J. Biol. Chem. 279(35):36490-36496 (2004).
Swingle, M.R., et al., J. Biol. Chem. 279(32):33992-33999 (2004).
Wechsler, T., et al., Proc. Natl. Acad. Sci. U.S.A. 101(5):1247-1252 (2004).
Zhou, G., et al., J. Biol. Chem. 279(45):46595-46605 (2004).
Huang, S., et al., J. Biol. Chem. 279(35):36490-36496 (2004).
Swingle, M.R., et al., J. Biol. Chem. 279(32):33992-33999 (2004).
Wechsler, T., et al., Proc. Natl. Acad. Sci. U.S.A. 101(5):1247-1252 (2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56879
NCBI Official Full Name
serine/threonine-protein phosphatase 5 isoform 1
NCBI Official Synonym Full Names
protein phosphatase 5, catalytic subunit
NCBI Official Symbol
PPP5C
NCBI Official Synonym Symbols
PP5; PPT; PPP5
NCBI Protein Information
serine/threonine-protein phosphatase 5
UniProt Protein Name
Serine/threonine-protein phosphatase 5
UniProt Gene Name
PPP5C
UniProt Synonym Gene Names
PPP5; PP5; PP-T; PPT
UniProt Entry Name
PPP5_HUMAN
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Product Notes
The PPP5C ppp5c (Catalog #AAA284645) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 445-475. The PP5 (PP5C) Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's PP5 (PP5C) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PPP5C ppp5c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP5 (PP5C), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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