IHC (Immunohiostchemistry)
(PPM1L antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PPM1L antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit PPM1L Polyclonal Antibody | anti-PPM1L antibody
PPM1L Antibody (C-term)
Gene Names
PPM1L; PP2CE; PPM1-LIKE; PP2C-epsilon
Reactivity
Human, mouse (Predicted Reactivity: Bovine)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PPM1L, Antibody; PPM1L Antibody (C-term); Protein phosphatase 1L; Protein phosphatase 1-like; Protein phosphatase 2C isoform epsilon; PP2C-epsilon; PPM1L; PP2CE; anti-PPM1L antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
215-244
Sequence Length
194
Applicable Applications for anti-PPM1L antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(PPM1L antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PPM1L antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(PPM1L antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PPM1L antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(PPM1L Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PPM1L antibody detected the PPM1L protein (arrow).)
WB (Western Blot)
(PPM1L Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PPM1L antibody detected the PPM1L protein (arrow).)
Related Product Information for anti-PPM1L antibody
PPM1L, or PP2CE, belongs to the PP2C group of
serine/threonine phosphatases, which are distinguished from other
phosphatases by their structure, absolute requirement for Mg(2+) or
Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate
stress-activated protein kinase (SAPK; see MIM 601158) signaling
cascades that respond to extracellular stimuli (Jin et al., 2004
[PubMed 15560375]).
serine/threonine phosphatases, which are distinguished from other
phosphatases by their structure, absolute requirement for Mg(2+) or
Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate
stress-activated protein kinase (SAPK; see MIM 601158) signaling
cascades that respond to extracellular stimuli (Jin et al., 2004
[PubMed 15560375]).
Product Categories/Family for anti-PPM1L antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Thean, L.F., et al. Genes Chromosomes Cancer 49(2):99-106(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Saito, S., et al. J. Biol. Chem. 283(10):6584-6593(2008)
Saito, J., et al. Biochem. J. 405(3):591-596(2007)
Thean, L.F., et al. Genes Chromosomes Cancer 49(2):99-106(2010)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Saito, S., et al. J. Biol. Chem. 283(10):6584-6593(2008)
Saito, J., et al. Biochem. J. 405(3):591-596(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41053
NCBI Official Full Name
protein phosphatase 1L
NCBI Official Synonym Full Names
protein phosphatase, Mg2+/Mn2+ dependent, 1L
NCBI Official Symbol
PPM1L
NCBI Official Synonym Symbols
PP2CE; PPM1-LIKE; PP2C-epsilon
NCBI Protein Information
protein phosphatase 1L
UniProt Protein Name
Protein phosphatase 1L
UniProt Gene Name
PPM1L
UniProt Synonym Gene Names
PP2CE; PP2C-epsilon
UniProt Entry Name
PPM1L_HUMAN
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Product Notes
The PPM1L ppm1l (Catalog #AAA286600) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 215-244. The PPM1L Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's PPM1L can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PPM1L ppm1l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPM1L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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