Rabbit PRKACB Polyclonal Antibody | anti-PRKACB antibody

PRKACB Antibody

Cat. Num. AAA233272

• Gene Names: PRKACB; PKACB; PKA C-beta
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: >95%, Protein G purified
• Synonyms: PRKACB, Antibody; PRKACB Antibody; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; EC 2.7.11.11; PRKACB; anti-PRKACB antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 358

• Applicable Applications for anti-PRKACB antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Immunogen: Recombinant Human cAMP-dependent protein kinase catalytic subunit beta protein (2-53AA)
• Conjugation: Non-conjugated
• Immunogen Species: Homo sapiens (Human)
• Target Names: PRKACB
• Research Area: Signal Transduction
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze

IF (Immunofluorescence)

(Immunofluorescent analysis of Hela cells using AAA233272 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human kidney tissue using AAA233272 at dilution of 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human brain tissue using AAA233272 at dilution of 1:100)

WB (Western Blot)

(Western BlotPositive WB detected in: A549 whole cell lysate, MCF-7 whole cell lysate, PC3 whole cell lysate, Rat brain tissue, Mouse brain tissueAll lanes: PRKACB antibody at 3 g/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 41, 47, 40, 42, 30, 37 KDaObserved band size: 41, 47 KDa)

Related Product Information for anti-PRKACB antibody

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

NCBI and Uniprot Product Information

• NCBI GI #: 338827753
• NCBI GeneID: 5567
• NCBI Accession #: NP_001229786.1
• NCBI GenBank Nucleotide #: NM_001242857.2
• UniProt Accession #: P22694; Q14VH1; Q59GC0; Q5BNE9; Q5BNF0; Q5BNF1; Q5BNF2; Q5BNF3; Q5CZ92; B1APG4; B4DKB0; B4E2Q1
• NCBI Official Full Name: cAMP-dependent protein kinase catalytic subunit beta isoform 4
• NCBI Official Synonym Full Names: protein kinase cAMP-activated catalytic subunit beta
• NCBI Official Symbol: PRKACB
• NCBI Official Synonym Symbols: PKACB; PKA C-beta
• NCBI Protein Information: cAMP-dependent protein kinase catalytic subunit beta
• UniProt Protein Name: cAMP-dependent protein kinase catalytic subunit beta
• UniProt Gene Name: PRKACB
• UniProt Synonym Gene Names: PKA C-beta