Rabbit PTF1A Polyclonal Antibody | anti-PTF1A antibody

PTF1A Antibody

Cat. Num. AAA233281

• Gene Names: PTF1A; PACA; PAGEN2; bHLHa29; PTF1-p48
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, ELISA
• Purity: >95%, Protein G purified
• Synonyms: PTF1A, Antibody; PTF1A Antibody; Pancreas transcription factor 1 subunit alpha; Class A basic helix-loop-helix protein 29; bHLHa29; Pancreas-specific transcription factor 1a; bHLH transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; PTF1-p48; PTF1A; BHLHA29; PTF1P48; anti-PTF1A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 328

• Applicable Applications for anti-PTF1A antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA
• Immunogen: Recombinant Human Pancreas transcription factor 1 subunit alpha protein (224-325AA)
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Immunogen Species: Homo sapiens (Human)
• Research Area: Neuroscience
• Target Names: PTF1A
• Preparation and Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

IHC (Immunohistochemisry)

(Immunofluorescent analysis of Hela cells using AAA233281 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human pancreatic tissue using AAA233281 at dilution of 1:100)

WB (Western Blot)

(Western BlotPositive WB detected in: Mouse brain tissue,Rat liver tissueAll lanes: PTF1A antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 35 KDaObserved band size: 35 KDa)

Related Product Information for anti-PTF1A antibody

Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.

NCBI and Uniprot Product Information

• NCBI GI #: 30039710
• NCBI GeneID: 256297
• NCBI Accession #: NP_835455.1
• NCBI GenBank Nucleotide #: NM_178161.2
• UniProt Accession #: Q7RTS3; Q9HC25
• NCBI Official Full Name: pancreas transcription factor 1 subunit alpha
• NCBI Official Synonym Full Names: pancreas specific transcription factor, 1a
• NCBI Official Symbol: PTF1A
• NCBI Official Synonym Symbols: PACA; PAGEN2; bHLHa29; PTF1-p48
• NCBI Protein Information: pancreas transcription factor 1 subunit alpha
• UniProt Protein Name: Pancreas transcription factor 1 subunit alpha
• UniProt Gene Name: PTF1A
• UniProt Synonym Gene Names: BHLHA29; PTF1P48; bHLHa29; PTF1-p48