FCM/FACS (Flow Cytometry)
(Rat MKP3 Antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Rat R MKP3 Polyclonal Antibody | anti-Dusp6 antibody
R MKP3 Antibody
Gene Names
Dusp6; Mkp3
Reactivity
Rat
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
R MKP3, Antibody; R MKP3 Antibody; Dual specificity protein phosphatase 6; Mitogen-activated protein kinase phosphatase 3; MAP kinase phosphatase 3; MKP-3; Dusp6; Mkp3; anti-Dusp6 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Rat MKP3 antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1~381 of rat MKP3.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Length
381
Applicable Applications for anti-Dusp6 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Recombinant Protein
Antigen Source
RAT
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(Rat MKP3 Antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(Rat MKP3 Antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(Western blot analysis of MKP3 (arrow) using rabbit polyclonal MKP3-His6 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MKP3 gene.)
WB (Western Blot)
(Western blot analysis of MKP3 (arrow) using rabbit polyclonal MKP3-His6 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MKP3 gene.)
Related Product Information for anti-Dusp6 antibody
Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36% identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis
Product Categories/Family for anti-Dusp6 antibody
References
Muda,M., et al. J. Biol. Chem. 271 (8), 4319-4326 (1996)
Mourey,R.J., et al. J. Biol. Chem. 271 (7), 3795-3802 (1996)
Mourey,R.J., et al. J. Biol. Chem. 271 (7), 3795-3802 (1996)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42319
NCBI Official Full Name
dual specificity protein phosphatase 6
NCBI Official Synonym Full Names
dual specificity phosphatase 6
NCBI Official Symbol
Dusp6
NCBI Official Synonym Symbols
Mkp3
NCBI Protein Information
dual specificity protein phosphatase 6
UniProt Protein Name
Dual specificity protein phosphatase 6
UniProt Gene Name
Dusp6
UniProt Synonym Gene Names
Mkp3; MAP kinase phosphatase 3; MKP-3
UniProt Entry Name
DUS6_RAT
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Product Notes
The Dusp6 dusp6 (Catalog #AAA290116) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The R MKP3 Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's R MKP3 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the Dusp6 dusp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "R MKP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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