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IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cell using RAN antibody. Blue: DAPI for nuclear staining.)
Rabbit RAN Polyclonal Antibody | anti-RAN antibody
RAN Antibody
Gene Names
RAN; TC4; Gsp1; ARA24
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Antigen affinity purification
Synonyms
RAN, Antibody; RAN Antibody; RAN; ARA24; Gsp1; TC4; anti-RAN antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
216
Applicable Applications for anti-RAN antibody
IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human RAN
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1156 / sc-1155 / sc-20802
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cell using RAN antibody. Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cell using RAN antibody. Blue: DAPI for nuclear staining.)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human stomach cancer using RAN antibody at dilution of 1:200 (400x lens).)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human stomach cancer using RAN antibody at dilution of 1:200 (400x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using RAN antibody at dilution of 1:200 (400x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast cancer using RAN antibody at dilution of 1:200 (400x lens).)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using RAN antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using RAN antibody.)
Related Product Information for anti-RAN antibody
Ran is a small GTPase of the Ras family that plays a central role in the spacial and temperal organization of eukaryotic cells. During interphase, Ran-GDP localizes to the cytoplasm and Ran-GTP to the nucleus. This polarized localization of Ran ensures its role in nuclear transport (1). During mitosis, Ran-GTP is chromatin associated, where it promotes spindle assembly and nuclear envolope formation (1, 2). In S phase, Ran-GTP associates with and inhibits MCM helicase, ensuring precise chromosomal DNA duplication during the cell cycle (3)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24,423 Da
NCBI Official Full Name
RAN, partial
NCBI Official Synonym Full Names
RAN, member RAS oncogene family
NCBI Official Symbol
RAN
NCBI Official Synonym Symbols
TC4; Gsp1; ARA24
NCBI Protein Information
GTP-binding nuclear protein Ran; GTPase Ran; OK/SW-cl.81; RanGTPase; androgen receptor-associated protein 24; guanosine triphosphatase Ran; member RAS oncogene family; ras-like protein TC4; ras-related nuclear protein
UniProt Protein Name
GTP-binding nuclear protein Ran
UniProt Gene Name
RAN
UniProt Synonym Gene Names
ARA24
UniProt Entry Name
RAN_HUMAN
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Product Notes
The RAN ran (Catalog #AAA166355) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAN Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RAN can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the RAN ran for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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