ICC (Immunocytochemistry)
(Immunocytochemistry of RAPTOR in L1210 cells with RAPTOR antibody at 10 ug/mL.)
Rabbit anti-Human, Mouse Raptor Polyclonal Antibody | anti-Raptor antibody
Raptor Antibody
Gene Names
RPTOR; KOG1; Mip1
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Raptor, Antibody; Raptor Antibody; anti-Raptor antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Raptor has multiple isoforms that may also be recognized by antibody.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1177
Applicable Applications for anti-Raptor antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide from near the amino-terminus of human Raptor.
Target Name
Raptor
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of RAPTOR in L1210 cells with RAPTOR antibody at 10 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of RAPTOR in L1210 cells with RAPTOR antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of Raptor in L1210 cell lysate with Raptor antibody at (A) 2 and (B) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of Raptor in L1210 cell lysate with Raptor antibody at (A) 2 and (B) 4 ug/mL.)
Related Product Information for anti-Raptor antibody
The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR activity resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. Raptor (regulatory associated protein of TOR) is a TOR-binding protein essential for TOR signaling in vivo. It acts as a TOR scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation. These substrates include the ribosomal protein S6 kinase (RP S6K) and the eukaryotic initiation factor 4E binding protein 4EBP1, proteins necessary for cell growth and proliferation and responsive to nutrient and mitogen levels. Raptor binds these proteins through a common 5 amino acid TOR-signaling (TOS) motif; mutation of this motif prevents the TOR-dependent phosphorylation of these proteins.
Product Categories/Family for anti-Raptor antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
131,515 Da
NCBI Official Full Name
regulatory-associated protein of mTOR isoform 2
NCBI Official Synonym Full Names
regulatory associated protein of MTOR, complex 1
NCBI Official Symbol
RPTOR
NCBI Official Synonym Symbols
KOG1; Mip1
NCBI Protein Information
regulatory-associated protein of mTOR
UniProt Protein Name
Regulatory-associated protein of mTOR
UniProt Gene Name
RPTOR
UniProt Synonym Gene Names
KIAA1303; RAPTOR; Raptor
UniProt Entry Name
RPTOR_HUMAN
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Product Notes
The Raptor rptor (Catalog #AAA303975) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Raptor Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Raptor can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Raptor rptor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Raptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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