Rabbit anti-Human, Mouse Raptor Polyclonal Antibody | anti-Rptor antibody

Raptor Antibody

Cat. Num. AAA39388

• Gene Names: Rptor; Rap; Raptor; mKIAA1303; 4932417H02Rik
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: Raptor Antibody is affinity chromatography purified via peptide column.
• Synonyms: Raptor, Antibody; Raptor Antibody; Raptor; Rap; mKIAA1303; 4932417H02Rik; Regulatory-associated protein of mTOR; regulatory associated protein of MTOR, complex 1; anti-Rptor antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Raptor has multiple isoforms that may also be recognized by antibody.
• Purity/Purification: Raptor Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1335

• Applicable Applications for anti-Rptor antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Raptor polyclonal antibody was raised against a 13 amino acid synthetic peptide from near the amino-terminus of human Raptor.
• Buffer: Raptor Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Raptor antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of Raptor in L1210 cells with Raptor antibody at 10 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of RAPTOR in L1210 cells with RAPTOR antibody at 10 μg/mL.)

Related Product Information for anti-Rptor antibody

Raptor Antibody: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR activity resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. Raptor (regulatory associated protein of TOR) is a TOR-binding protein essential for TOR signaling in vivo. It acts as a TOR scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation. These substrates include the ribosomal protein S6 kinase (RP S6K) and the eukaryotic initiation factor 4E binding protein 4EBP1, proteins necessary for cell growth and proliferation and responsive to nutrient and mitogen levels. Raptor binds these proteins through a common 5 amino acid TOR-signaling (TOS) motif; mutation of this motif prevents the TOR-dependent phosphorylation of these proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 46577497
• NCBI GeneID: 74370
• UniProt Accession #: Q8K4Q0; Q8C9W9; Q8CBY4; Q8CDY8; Q9D4H3
• Molecular Weight: 33,651 Da
• NCBI Official Full Name: Regulatory-associated protein of mTOR
• NCBI Official Synonym Full Names: regulatory associated protein of MTOR, complex 1
• NCBI Official Symbol: Rptor
• NCBI Official Synonym Symbols: Rap; Raptor; mKIAA1303; 4932417H02Rik
• NCBI Protein Information: regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein
• UniProt Protein Name: Regulatory-associated protein of mTOR
• UniProt Gene Name: Rptor
• UniProt Synonym Gene Names: Raptor; Raptor
• UniProt Entry Name: RPTOR_MOUSE