IHC (Immunohiostchemistry)
(RC3H1 Antibody (C-term) (AAA287531)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RC3H1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit RC3H1 Polyclonal Antibody | anti-RC3H1 antibody
RC3H1 Antibody (C-term)
Gene Names
RC3H1; RNF198; ROQUIN
Reactivity
Human (Predicted Reactivity: Mouse, Xenopus)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
RC3H1, Antibody; RC3H1 Antibody (C-term); Roquin-1; Roquin; RING finger and C3H zinc finger protein 1; RING finger and CCCH-type zinc finger domain-containing protein 1; RING finger protein 198; RC3H1; KIAA2025; RNF198; anti-RC3H1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Xenopus)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This RC3H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1015-1043 amino acids from the C-terminal region of human RC3H1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
1015-1043
Sequence Length
1,125
Applicable Applications for anti-RC3H1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(RC3H1 Antibody (C-term) (AAA287531)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RC3H1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(RC3H1 Antibody (C-term) (AAA287531)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RC3H1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(RC3H1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RC3H1 antibody detected the RC3H1 protein (arrow).)
WB (Western Blot)
(RC3H1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RC3H1 antibody detected the RC3H1 protein (arrow).)
Related Product Information for anti-RC3H1 antibody
RC3H1, or roquin, encodes a highly conserved member of the
RING type ubiquitin ligase protein family (Vinuesa et al., 2005
[PubMed 15917799]). The roquin protein is distinguished by the
presence of a CCCH zinc finger found in RNA-binding proteins, and
localization to cytosolic RNA granules implicated in regulating
mRNA translation and stability.
RING type ubiquitin ligase protein family (Vinuesa et al., 2005
[PubMed 15917799]). The roquin protein is distinguished by the
presence of a CCCH zinc finger found in RNA-binding proteins, and
localization to cytosolic RNA granules implicated in regulating
mRNA translation and stability.
References
Vinuesa, C.G., et al. Nature 435(7041):452-458(2005)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
125736
NCBI Official Full Name
roquin-1 isoform b
NCBI Official Synonym Full Names
ring finger and CCCH-type domains 1
NCBI Official Symbol
RC3H1
NCBI Official Synonym Symbols
RNF198; ROQUIN
NCBI Protein Information
roquin-1
UniProt Protein Name
Roquin-1
UniProt Gene Name
RC3H1
UniProt Synonym Gene Names
KIAA2025; RNF198; Roquin
UniProt Entry Name
RC3H1_HUMAN
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Product Notes
The RC3H1 rc3h1 (Catalog #AAA287531) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1015-1043. The RC3H1 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's RC3H1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the RC3H1 rc3h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RC3H1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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