IF (Immunofluorescence)
(Immunofluorescence of RC3H1 in human small intestine tissue with RC3H1 antibody at 20 μg/ml.)
Rabbit RC3H1 Polyclonal Antibody | anti-RC3H1 antibody
RC3H1 Antibody
Gene Names
RC3H1; RNF198; ROQUIN
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
RC3H1 Antibody is affinity chromatography purified via peptide column.
Synonyms
RC3H1, Antibody; RC3H1 Antibody; RC3H1; RNF198; ROQUIN; KIAA2025; Roquin-1; RING finger and C3H zinc finger protein 1; Roquin; ring finger and CCCH-type domains 1; anti-RC3H1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least three isoforms of RC3H1 are known to exist; this antibody will detect all three isoforms.
Purity/Purification
RC3H1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1133
Applicable Applications for anti-RC3H1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal RC3H1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RC3H1.
Buffer
RC3H1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
RC3H1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of RC3H1 in human small intestine tissue with RC3H1 antibody at 20 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of RC3H1 in human small intestine tissue with RC3H1 antibody at 20 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of RC3H1 in human small intestine tissue with RC3H1 antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of RC3H1 in human small intestine tissue with RC3H1 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of RC3H1 in HeLa cell lysate with RC3H1 antibody at 1 μg/mL)
WB (Western Blot)
(Western blot analysis of RC3H1 in HeLa cell lysate with RC3H1 antibody at 1 μg/mL)
Related Product Information for anti-RC3H1 antibody
RC3H1 Antibody: The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
125 kDa
NCBI Official Full Name
roquin-1 isoform b
NCBI Official Synonym Full Names
ring finger and CCCH-type domains 1
NCBI Official Symbol
RC3H1
NCBI Official Synonym Symbols
RNF198; ROQUIN
NCBI Protein Information
roquin-1; RING finger protein 198; RING finger and C3H zinc finger protein 1; probable E3 ubiquitin-protein ligase Roquin; RING finger and CCCH-type zinc finger domain-containing protein 1
UniProt Protein Name
Roquin-1
UniProt Gene Name
RC3H1
UniProt Synonym Gene Names
KIAA2025; RNF198; Roquin
UniProt Entry Name
RC3H1_HUMAN
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Product Notes
The RC3H1 rc3h1 (Catalog #AAA40496) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RC3H1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RC3H1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RC3H1 rc3h1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RC3H1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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