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WB (Western Blot)
(Western blot analysis of ROCK1 in 293 cell lysate with ROCK1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human Rho Kinase / ROCK1 Polyclonal Antibody | anti-ROCK1 antibody
Rabbit Polyclonal to Human Rho Kinase / ROCK1
Gene Names
ROCK1; ROCK-I; P160ROCK
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
Rho Kinase / ROCK1, Antibody; Rabbit Polyclonal to Human Rho Kinase / ROCK1; Anti-Rho Kinase / ROCK1 Antibody (N-Terminus) IHC-plus; ROCK1; p160 Rho-associated kinase; p160ROCK; p160 ROCK-1; p160-ROCK; p160RhoK; Rho-associated kinase; RockI; Rok; Rok alpha; Rho-alpha kinase; p160 rho-kinase; Rho kinase; ROCK-I; Rokalpha; Human Rho Kinase; anti-ROCK1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human ROCK1. ROCK1 antibody is predicted to not cross-react with other ROCK protein family members.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
1354
Applicable Applications for anti-ROCK1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
A 15 amino acid peptide near the amino terminus of human ROCK1
Immunogen Type
Synthetic peptide
Antigen Modification
N-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
WB (Western Blot)
(Western blot analysis of ROCK1 in 293 cell lysate with ROCK1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of ROCK1 in 293 cell lysate with ROCK1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
ICC (Immunocytochemistry)
(Immunocytochemistry of ROCK1 in 293 cells with ROCK1 antibody at 10 ug/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of ROCK1 in 293 cells with ROCK1 antibody at 10 ug/ml.)
IF (Immunofluorescence)
(Immunofluorescence of ROCK1 in 293 cells with ROCK1 antibody at 20 ug/ml.)
IF (Immunofluorescence)
(Immunofluorescence of ROCK1 in 293 cells with ROCK1 antibody at 20 ug/ml.)
IHC (Immunohistochemistry)
(Anti-ROCK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-ROCK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-ROCK1 antibody
ROCK1 is a ROCK protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. ROCK1 mediates Rho-induced assembly of focal adhesions and stress fibers. ROCK1, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. In addition, p160ROCK is required for centrosome positioning and centrosome-dependent exit from mitosis.
Product Categories/Family for anti-ROCK1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
158,175 Da
NCBI Official Full Name
rho-associated protein kinase 1
NCBI Official Synonym Full Names
Rho-associated, coiled-coil containing protein kinase 1
NCBI Official Symbol
ROCK1
NCBI Official Synonym Symbols
ROCK-I; P160ROCK
NCBI Protein Information
rho-associated protein kinase 1; p160-ROCK; Rho kinase; p160 ROCK-1; renal carcinoma antigen NY-REN-35; rho-associated, coiled-coil-containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase I
UniProt Protein Name
Rho-associated protein kinase 1
UniProt Gene Name
ROCK1
UniProt Synonym Gene Names
ROCK-I; p160ROCK
UniProt Entry Name
ROCK1_HUMAN
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Product Notes
The ROCK1 rock1 (Catalog #AAA52147) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human Rho Kinase / ROCK1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Rho Kinase / ROCK1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ROCK1 rock1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rho Kinase / ROCK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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