IHC (Immunohiostchemistry)
(RIPK1 Antibody (N-term) (AAA289559)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIPK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human RIPK1 Polyclonal Antibody | anti-RIPK1 antibody
RIPK1 Antibody (N-term)
Gene Names
RIPK1; RIP; RIP1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
RIPK1, Antibody; RIPK1 Antibody (N-term); Receptor-interacting serine/threonine-protein kinase 1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1; Serine/threonine-protein kinase RIP; RIPK1; RIP; RIP1; anti-RIPK1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This RIPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the N-terminal region of human RIPK1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
152-180
Sequence Length
625
Applicable Applications for anti-RIPK1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(RIPK1 Antibody (N-term) (AAA289559)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIPK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(RIPK1 Antibody (N-term) (AAA289559)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIPK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(RIPK1 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RIPK1 antibody detected the RIPK1 protein (arrow).)
WB (Western Blot)
(RIPK1 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RIPK1 antibody detected the RIPK1 protein (arrow).)
Related Product Information for anti-RIPK1 antibody
Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains.
Product Categories/Family for anti-RIPK1 antibody
References
Kim, S., et al. Cancer Sci. 101(11):2425-2429(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Chae, Y.S., et al. J. Cancer Res. Clin. Oncol. (2010) In press :
Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):251-257(2010)
Vandenabeele, P., et al. Sci Signal 3 (115), RE4 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Chae, Y.S., et al. J. Cancer Res. Clin. Oncol. (2010) In press :
Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):251-257(2010)
Vandenabeele, P., et al. Sci Signal 3 (115), RE4 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75931
NCBI Official Full Name
receptor-interacting serine/threonine-protein kinase 1
NCBI Official Synonym Full Names
receptor (TNFRSF)-interacting serine-threonine kinase 1
NCBI Official Symbol
RIPK1
NCBI Official Synonym Symbols
RIP; RIP1
NCBI Protein Information
receptor-interacting serine/threonine-protein kinase 1
UniProt Protein Name
Receptor-interacting serine/threonine-protein kinase 1
UniProt Gene Name
RIPK1
UniProt Synonym Gene Names
RIP; RIP1; RIP-1
UniProt Entry Name
RIPK1_HUMAN
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Product Notes
The RIPK1 ripk1 (Catalog #AAA289559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 152-180. The RIPK1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RIPK1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the RIPK1 ripk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RIPK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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