WB (Western Blot)
(Western blot analysis of extracts from RH-30 cells, using Phospho-RYR3(Ser160) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)
Rabbit anti-Human, Mouse RYR3 Polyclonal Antibody | anti-RYR3 antibody
Phospho-RYR3(Ser160) Antibody
Gene Names
RYR3; RYR-3
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Synonyms
RYR3, Antibody; Phospho-RYR3(Ser160) Antibody; Brain ryanodine receptor calcium release channel; Brain ryanodine receptor-calcium release channel; Brain type ryanodine receptor; Brain-type ryanodine receptor; HBRR; Ryanodine receptor 3; RYR 3; RYR-3; RyR3; RYR3_HUMAN; anti-RYR3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Phospho-RYR3(Ser160) antibody detects endogenous levels of RYR3 only when phosphorylated as ser160.
Purity/Purification
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
4870
Applicable Applications for anti-RYR3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human RYR3 around the phosphorylation site of Ser160.
Conjugation
Unconjugated
Epitope
Phospho Ser160
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from RH-30 cells, using Phospho-RYR3(Ser160) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from RH-30 cells, using Phospho-RYR3(Ser160) Antibody. Lane1 was treated with phospho-blocking peptide, Lane2 was treated with non-phospho-blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts of RH-30 cells, using Phospho-RYR3(Ser160) Antibody.)
WB (Western Blot)
(Western blot analysis of extracts of RH-30 cells, using Phospho-RYR3(Ser160) Antibody.)
IHC (Immunohistochemistry)
(AAA321289 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
IHC (Immunohistochemistry)
(AAA321289 at 1/100 staining Human thyroid cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Related Product Information for anti-RYR3 antibody
Function: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca2+ release by other calcium channels. Calcium channel that mediates Ca2+-induced Ca2+ release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling.
Subunit Structure: Homotetramer. Heterotetramer with RYR2. Interacts with CALM (By similarity). Interacts with FKBP1A. Interacts with SELENON (By similarity).
Similarity: The calcium release channel activity resides in the C-terminal region while the remaining part of the protein resides in the cytoplasm. Belongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily.
Subunit Structure: Homotetramer. Heterotetramer with RYR2. Interacts with CALM (By similarity). Interacts with FKBP1A. Interacts with SELENON (By similarity).
Similarity: The calcium release channel activity resides in the C-terminal region while the remaining part of the protein resides in the cytoplasm. Belongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
550 kDa
NCBI Official Full Name
ryanodine receptor 3 isoform 1
NCBI Official Synonym Full Names
ryanodine receptor 3
NCBI Official Symbol
RYR3
NCBI Official Synonym Symbols
RYR-3
NCBI Protein Information
ryanodine receptor 3
UniProt Protein Name
Ryanodine receptor 3
UniProt Gene Name
RYR3
UniProt Synonym Gene Names
HBRR; RYR-3; RyR3
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Product Notes
The RYR3 ryr3 (Catalog #AAA321289) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-RYR3(Ser160) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RYR3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the RYR3 ryr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RYR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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