Rabbit SCARB1 Polyclonal Antibody | anti-SCARB1 antibody

SCARB1 Antibody

Cat. Num. AAA39279

• Gene Names: SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: SCARB1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: SCARB1, Antibody; SCARB1 Antibody; SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; Scavenger receptor class B member 1; CD36 and LIMPII analogous 1; scavenger receptor class B, member 1; anti-SCARB1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: SCARB1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 552

• Applicable Applications for anti-SCARB1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: SCARB1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SCARB1.
• Buffer: SCARB1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: SCARB1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of SCARB1 in Human Spleen tissue with SCARB1 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of SCARB1 in human spleen tissue with SCARB1 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of SCARB1 in human spleen tissue lysate with SCARB1 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-SCARB1 antibody

SCARB1 Antibody: Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.

NCBI and Uniprot Product Information

• NCBI GI #: 37999904
• NCBI GeneID: 949
• UniProt Accession #: Q8WTV0; Q14016; Q52LZ5; Q6KFX4; F8W8N0
• Molecular Weight: 56,170 Da
• NCBI Official Full Name: Scavenger receptor class B member 1
• NCBI Official Synonym Full Names: scavenger receptor class B, member 1
• NCBI Official Symbol: SCARB1
• NCBI Official Synonym Symbols: CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6
• NCBI Protein Information: scavenger receptor class B member 1; CD36 and LIMPII analogous 1; scavenger receptor class B type III; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1
• UniProt Protein Name: Scavenger receptor class B member 1
• UniProt Gene Name: SCARB1
• UniProt Synonym Gene Names: CD36L1; CLA1; SRB1; CLA-1
• UniProt Entry Name: SCRB1_HUMAN