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product-image-AAA305093_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded rat ovary using SMPD1 / ASM at dilution of 1:100 (40x lens).)

Rabbit SMPD1 Polyclonal Antibody | anti-SMPD1 antibody

SMPD1 antibody

Gene Names
SMPD1; ASM; NPD; ASMASE
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
SMPD1, Antibody; SMPD1 antibody; ASM; NPD; ASMASE; anti-SMPD1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total SMPD1 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
631
Applicable Applications for anti-SMPD1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human SMPD1.
Target Name
SMPD1
Preparation and Storage
Store at -20 degree C

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded rat ovary using SMPD1 / ASM at dilution of 1:100 (40x lens).)

product-image-AAA305093_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded rat ovary using SMPD1 / ASM at dilution of 1:100 (40x lens).)

IF (Immunofluorescence)

(Immunofluorescence analysis of HeLa cell using SMPD1 antibody. Blue: DAPI for nuclear staining.)

product-image-AAA305093_IF13.jpg IF (Immunofluorescence) (Immunofluorescence analysis of HeLa cell using SMPD1 antibody. Blue: DAPI for nuclear staining.)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using SMPD1/ASM at 1:1000 dilution.)

product-image-AAA305093_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines, using SMPD1/ASM at 1:1000 dilution.)
Related Product Information for anti-SMPD1 antibody
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Product Categories/Family for anti-SMPD1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69 kd
NCBI Official Full Name
sphingomyelin phosphodiesterase isoform 1
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 1, acid lysosomal
NCBI Official Symbol
SMPD1
NCBI Official Synonym Symbols
ASM; NPD; ASMASE
NCBI Protein Information
sphingomyelin phosphodiesterase
UniProt Protein Name
Sphingomyelin phosphodiesterase
UniProt Gene Name
SMPD1
UniProt Synonym Gene Names
ASM; aSMase
UniProt Entry Name
ASM_HUMAN

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Product Notes

The SMPD1 smpd1 (Catalog #AAA305093) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SMPD1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SMPD1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SMPD1 smpd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMPD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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