IHC (Immunohiostchemistry)
(TERF2 Antibody (Center) (AAA287089)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TERF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human TERF2 Polyclonal Antibody | anti-TERF2 antibody
TERF2 Antibody (Center)
Gene Names
TERF2; TRF2; TRBF2
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TERF2, Antibody; TERF2 Antibody (Center); Telomeric repeat-binding factor 2; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein; TERF2; TRBF2; TRF2; anti-TERF2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TERF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the Central region of human TERF2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
308-337
Sequence Length
293
Applicable Applications for anti-TERF2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(TERF2 Antibody (Center) (AAA287089)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TERF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(TERF2 Antibody (Center) (AAA287089)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TERF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(TERF2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TERF2 antibody detected the TERF2 protein (arrow).)
WB (Western Blot)
(TERF2 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TERF2 antibody detected the TERF2 protein (arrow).)
Related Product Information for anti-TERF2 antibody
This gene encodes a telomere specific protein, TERF2,
which is a component of the telomere nucleoprotein complex. This
protein is present at telomeres in metaphase of the cell cycle, is
a second negative regulator of telomere length and plays a key role
in the protective activity of telomeres. While having similar
telomere binding activity and domain organization, TERF2 differs
from TERF1 in that its N terminus is basic rather than acidic.
which is a component of the telomere nucleoprotein complex. This
protein is present at telomeres in metaphase of the cell cycle, is
a second negative regulator of telomere length and plays a key role
in the protective activity of telomeres. While having similar
telomere binding activity and domain organization, TERF2 differs
from TERF1 in that its N terminus is basic rather than acidic.
Product Categories/Family for anti-TERF2 antibody
References
Prescott, J., et al. Cancer 116(18):4275-4282(2010)
Ye, J., et al. Cell 142(2):230-242(2010)
Bombarde, O., et al. EMBO J. 29(9):1573-1584(2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Giannone, R.J., et al. PLoS ONE 5 (8), E12407 (2010) :
Ye, J., et al. Cell 142(2):230-242(2010)
Bombarde, O., et al. EMBO J. 29(9):1573-1584(2010)
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Giannone, R.J., et al. PLoS ONE 5 (8), E12407 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59594
NCBI Official Full Name
telomeric repeat-binding factor 2
NCBI Official Synonym Full Names
telomeric repeat binding factor 2
NCBI Official Symbol
TERF2
NCBI Official Synonym Symbols
TRF2; TRBF2
NCBI Protein Information
telomeric repeat-binding factor 2
UniProt Protein Name
Telomeric repeat-binding factor 2
UniProt Gene Name
TERF2
UniProt Synonym Gene Names
TRBF2; TRF2
UniProt Entry Name
TERF2_HUMAN
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Product Notes
The TERF2 terf2 (Catalog #AAA287089) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 308-337. The TERF2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TERF2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the TERF2 terf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TERF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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