IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA119529 at dilution 1:100)
Rabbit anti-Human TFIIH basal transcription factor complex helicase XPD Polyclonal Antibody | anti-ERCC2 antibody
Rabbit anti-human TFIIH basal transcription factor complex helicase XPD subunit polyclonal Antibody(ERCC2)
Gene Names
ERCC2; EM9; TTD; XPD; TTD1; COFS2; TFIIH
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
TFIIH basal transcription factor complex helicase XPD, Antibody; Rabbit anti-human TFIIH basal transcription factor complex helicase XPD subunit polyclonal Antibody(ERCC2); Basic transcription factor 2 80 kDa subunit; BTF2 p80; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH 80 kDa subunit; TFIIH p80; Xeroderma pigmentosum group D-complementing protein; ERCC2; XPD; XPDC; anti-ERCC2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
760
Applicable Applications for anti-ERCC2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6858 / sc-20696
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA119529 at dilution 1:100)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA119529 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human skin using AAA119529 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human skin using AAA119529 at dilution 1:100)
WB (Western Blot)
(All lanes: TFIIH basal transcription factor complex helicase XPD subunit antibody at 2ug/mlLane 1:293T whole cell lysateLane 2:K562 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 87,47 kDaObserved band size: 87 kDa)
WB (Western Blot)
(All lanes: TFIIH basal transcription factor complex helicase XPD subunit antibody at 2ug/mlLane 1:293T whole cell lysateLane 2:K562 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 87,47 kDaObserved band size: 87 kDa)
Related Product Information for anti-ERCC2 antibody
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,274 Da
NCBI Official Full Name
TFIIH basal transcription factor complex helicase XPD subunit isoform 1
NCBI Official Synonym Full Names
excision repair cross-complementation group 2
NCBI Official Symbol
ERCC2
NCBI Official Synonym Symbols
EM9; TTD; XPD; TTD1; COFS2; TFIIH
NCBI Protein Information
TFIIH basal transcription factor complex helicase XPD subunit
UniProt Protein Name
TFIIH basal transcription factor complex helicase XPD subunit
UniProt Gene Name
ERCC2
UniProt Synonym Gene Names
XPD; XPDC; BTF2 p80; TFIIH 80 kDa subunit; TFIIH p80
UniProt Entry Name
ERCC2_HUMAN
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Product Notes
The ERCC2 ercc2 (Catalog #AAA119529) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human TFIIH basal transcription factor complex helicase XPD subunit polyclonal Antibody(ERCC2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TFIIH basal transcription factor complex helicase XPD can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ERCC2 ercc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TFIIH basal transcription factor complex helicase XPD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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