WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TIM-3/HAVCR2 Polyclonal Antibody at 1:1000 dilution.)
Rabbit TIM-3/HAVCR2 Polyclonal Antibody | anti-TIM-3/HAVCR2 antibody
TIM-3/HAVCR2 Polyclonal Antibody
Gene Names
Havcr2; Tim3; TIM-3; Timd3
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purification
Synonyms
TIM-3/HAVCR2, Antibody; TIM-3/HAVCR2 Polyclonal Antibody; Tim; TIM-; Tim3; Timd; TIM-3; Timd3; anti-TIM-3/HAVCR2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-TIM-3/HAVCR2 antibody
WB (Western Blot)
Immunogen
Recombinant fusion protein of mouse TIM-3/HAVCR2
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TIM-3/HAVCR2 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TIM-3/HAVCR2 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TIM-3/HAVCR2 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using TIM-3/HAVCR2 Polyclonal Antibody at 1:1000 dilution.)
Related Product Information for anti-TIM-3/HAVCR2 antibody
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis virus cellular receptor 2 (HAVCR2), isa transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important rolein the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, anddendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosisof apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interactionwith phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressivefunctions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with anagonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is alsoregarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as twoimportant coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction orexhaustion associated with chronic HBV infection including HBV-related HCC.
Product Categories/Family for anti-TIM-3/HAVCR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,934 Da
NCBI Official Full Name
hepatitis A virus cellular receptor 2 homolog
NCBI Official Synonym Full Names
hepatitis A virus cellular receptor 2
NCBI Official Symbol
Havcr2
NCBI Official Synonym Symbols
Tim3; TIM-3; Timd3
NCBI Protein Information
hepatitis A virus cellular receptor 2 homolog; TIMD-3; HAVcr-2; T-cell membrane protein 3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3
UniProt Protein Name
Hepatitis A virus cellular receptor 2 homolog
UniProt Gene Name
Havcr2
UniProt Synonym Gene Names
Tim3; Timd3; HAVcr-2; TIMD-3
UniProt Entry Name
HAVR2_MOUSE
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Product Notes
The TIM-3/HAVCR2 havcr2 (Catalog #AAA179559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TIM-3/HAVCR2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TIM-3/HAVCR2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the TIM-3/HAVCR2 havcr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIM-3/HAVCR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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