WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using TIRAP antibody.)
Rabbit TIRAP Polyclonal Antibody | anti-TIRAP antibody
TIRAP Rabbit Polyclonal Antibody
Gene Names
TIRAP; Mal; wyatt; BACTS1; MyD88-2
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
TIRAP, Antibody; TIRAP Rabbit Polyclonal Antibody; TIRAP; BACTS1; Mal; MyD88-2; wyatt; anti-TIRAP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applicable Applications for anti-TIRAP antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant fusion protein of human TIRAP (NP_001034750.1).
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using TIRAP antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using TIRAP antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using TIRAP antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using TIRAP antibody.)
Related Product Information for anti-TIRAP antibody
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
Product Categories/Family for anti-TIRAP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,883 Da
NCBI Official Full Name
toll/interleukin-1 receptor domain-containing adapter protein isoform a
NCBI Official Synonym Full Names
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
NCBI Official Symbol
TIRAP
NCBI Official Synonym Symbols
Mal; wyatt; BACTS1; MyD88-2
NCBI Protein Information
toll/interleukin-1 receptor domain-containing adapter protein; adapter protein wyatt; adaptor protein Wyatt; MyD88 adapter-like protein; Toll-like receptor adaptor protein
UniProt Protein Name
Toll/interleukin-1 receptor domain-containing adapter protein
UniProt Gene Name
TIRAP
UniProt Synonym Gene Names
MAL; TIR domain-containing adapter protein; MyD88-2
UniProt Entry Name
TIRAP_HUMAN
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Product Notes
The TIRAP tirap (Catalog #AAA313324) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TIRAP Rabbit Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TIRAP can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the TIRAP tirap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIRAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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