IHC (Immunohiostchemistry)
(Immunohistochemistry of TIRAP in human heart tissue with TIRAP antibody at 20 ug/mL.)
Rabbit anti-Human TIRAP Polyclonal Antibody | anti-TIRAP antibody
TIRAP Antibody
Gene Names
TIRAP; Mal; wyatt; BACTS1; MyD88-2
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Ion exchange chromatography purified
Synonyms
TIRAP, Antibody; TIRAP Antibody; MAL; anti-TIRAP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Ion exchange chromatography purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
235
Applicable Applications for anti-TIRAP antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a peptide corresponding to amino acids near the middle of human TIRAP.
Target Name
TIRAP
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of TIRAP in human heart tissue with TIRAP antibody at 20 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TIRAP in human heart tissue with TIRAP antibody at 20 ug/mL.)
WB (Western Blot)
(Western blot analysis of TIRAP in MCF-7 cell lysate with TIRAP antibody at 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of TIRAP in MCF-7 cell lysate with TIRAP antibody at 4 ug/mL.)
Related Product Information for anti-TIRAP antibody
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors. In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling. Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-kB and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling.
Product Categories/Family for anti-TIRAP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
27,948 Da
NCBI Official Full Name
TIR domain containing adaptor protein TIRAP
NCBI Official Synonym Full Names
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
NCBI Official Symbol
TIRAP
NCBI Official Synonym Symbols
Mal; wyatt; BACTS1; MyD88-2
NCBI Protein Information
toll/interleukin-1 receptor domain-containing adapter protein
UniProt Protein Name
Toll/interleukin-1 receptor domain-containing adapter protein
UniProt Gene Name
TIRAP
UniProt Synonym Gene Names
MAL; TIR domain-containing adapter protein; MyD88-2
UniProt Entry Name
TIRAP_HUMAN
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Product Notes
The TIRAP tirap (Catalog #AAA301253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TIRAP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TIRAP can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TIRAP tirap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TIRAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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