IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human colon cancer using AAA231395 at dilution 1:100)
Rabbit anti-Human, Mouse TMED10 Polyclonal Antibody | anti-TMED10 antibody
TMED10 Antibody
Gene Names
TMED10; p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
TMED10, Antibody; TMED10 Antibody; Transmembrane emp24 domain-containing protein 10; 21 kDa transmembrane-trafficking protein; S31III125; S31I125; Tmp-21-I; Transmembrane protein Tmp21; p23; p24 family protein delta-1; p24delta1; p24delta; TMED10; TMP21; anti-TMED10 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
219
Applicable Applications for anti-TMED10 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Species
Human
Immunogen
Recombinant human Transmembrane emp24 domain-containing protein 10 protein (35-190AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68398
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human colon cancer using AAA231395 at dilution 1:100)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human colon cancer using AAA231395 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human testis tissue using AAA231395 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human testis tissue using AAA231395 at dilution 1:100)
WB (Western Blot)
(Western blotAll lanes: TMED10antibody at 4.88ug/mlLane 1 : Hela whole cell lysateLane 2 : Mouse liver tissueLane 3 : Mouse lung tissueLane 4 : 293T whole cell lysateLane 5 : NIH/3T3 whole cell lysateLane 6 : U87 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 25 kDaObserved band size: 25 kDa)
WB (Western Blot)
(Western blotAll lanes: TMED10antibody at 4.88ug/mlLane 1 : Hela whole cell lysateLane 2 : Mouse liver tissueLane 3 : Mouse lung tissueLane 4 : 293T whole cell lysateLane 5 : NIH/3T3 whole cell lysateLane 6 : U87 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 25 kDaObserved band size: 25 kDa)
Related Product Information for anti-TMED10 antibody
Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1 (By similarity). In COPI vesicle-mediated retrograde transport involved in the biogenesis of COPI vesicles and vesicle coat recruitment. On Golgi membranes, acts as primary receptor for ARF1-GDP which is involved in COPI-vesicle formation. Increases coatomer-dependent GTPase-activating activity of ARFGAP2. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2LR1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Involved in trafficking of amyloid beta A4 protein and soluble APP-beta release (independent of modulation of gamma-secretase activity). As part of the presenilin-dependent gamma-secretase complex regulates gamma-cleavages of the amyloid beta A4 protein to yield amyloid-beta 40 (Abeta40). Involved in organization of the Golgi apparatus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,976 Da
NCBI Official Full Name
transmembrane emp24 domain-containing protein 10
NCBI Official Synonym Full Names
transmembrane p24 trafficking protein 10
NCBI Official Symbol
TMED10
NCBI Official Synonym Symbols
p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)
NCBI Protein Information
transmembrane emp24 domain-containing protein 10
UniProt Protein Name
Transmembrane emp24 domain-containing protein 10
UniProt Gene Name
TMED10
UniProt Synonym Gene Names
TMP21; S31I125; p24delta1
UniProt Entry Name
TMEDA_HUMAN
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Product Notes
The TMED10 tmed10 (Catalog #AAA231395) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMED10 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TMED10 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TMED10 tmed10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMED10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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